transition metal catalyzed pyridine synthesis

Transition Metal Catalyzed Pyridine Synthesis
Author: Xiao-Feng Wu
Publisher: Elsevier
Release Date: 2016-02-07
Pages: 90
ISBN:
Available Language: English, Spanish, And French
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Transition Metal-Catalyzed Pyridine Synthesis provides an overview of pyridines, describing properties of these heterocycle compounds and describing traditional synthetic procedures for them. The book then explores catalyzed procedures for pyridine synthesis in greater detail and depth than is currently available in published Review articles. The short series Transition Metal-Catalyzed Heterocycles Synthesis, authored by Xiao-Feng Wu, summarizes recent achievements on heterocycles synthesis with transition metal as the catalysts, with each volume dedicated to one heterocycle compound. Brief, focused review of this active research area, Pyridine synthesis via transition metal catalysis Useful coverage of Pyridine properties and both intermolecular and intramolecular cyclization Volume Two in Elsevier’s short work series, "Transition Metal-Catalyzed Heterocycles Synthesis"

Transition Metal Catalyzed Heterocycle Synthesis Via C H Activation
Author: Xiao-Feng Wu
Publisher: John Wiley & Sons
Release Date: 2016-03-07
Pages: 600
ISBN:
Available Language: English, Spanish, And French
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Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.

Heterocyclic Chemistry In Drug Discovery
Author: Jie Jack Li
Publisher: John Wiley & Sons
Release Date: 2013-04-26
Pages: 720
ISBN:
Available Language: English, Spanish, And French
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Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own academic and industrial laboratory experience, helping readers avoid common pitfalls. Heterocyclic Chemistry in Drug Discovery is ideal for readers who want to fully realize the almost limitless potential to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features: Several case studies illustrating the role and application of 3, 4, 5, and 6+ heterocyclic ring systems in drug discovery Step-by-step descriptions of synthetic methods and practical techniques Examination of the physical properties for each heterocycle, including NMR data and quantum calculations Detailed explanations of the complexity and intricacies of reactivity and stability for each class of heterocycles Heterocyclic Chemistry in Drug Discovery is recommended as a textbook for organic and medicinal chemistry courses, particularly those emphasizing heterocyclic chemistry. The text also serves as a guide for medicinal and process chemists in the pharmaceutical industry, offering them new insights and new paths to explore for effective drug discovery.

Progress In Heterocyclic Chemistry
Author: Gordon W. Gribble
Publisher: Elsevier
Release Date: 2009-09-03
Pages: 572
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Progress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on emerging topics of particular interest to heterocyclic chemists. The chapters in Volume 21 constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2008. Additional articles in this volume review "Biocatalytic approaches to chiral heterocycles" and "Ring-expanded (‘fat’) purines and their nucleoside/nucleotide analogues as broad-spectrum therapeutics." As with previous volumes in the series, Volume 21 apprises academic/industrial chemists and advanced students of developments in heterocyclic chemistry in a convenient format. * Covers the heterocyclic literature published in 2008 * Includes specialized reviews * Features contributions from leading researchers in their fields

Transition Metals For Organic Synthesis
Author: Matthias Beller
Publisher: Wiley-VCH
Release Date: 1998-09-17
Pages: 1120
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This two volume set presents contemporary research and application in the economically and scientifically important area of transition metals for organic synthesis and fine chemicals production.

Aspects Of Homogeneous Catalysis
Author: R. Ugo
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
Pages: 356
ISBN:
Available Language: English, Spanish, And French
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1. INTRODUCTION Although quite spectacular results have been obtained in the last few decades in the field of homogeneous transition metal catalyzed transformations of olefins and alkynes [1], reactions which could lead to heterocycles have been partly neglected. An obvious reason for this is that substrates containing heteroatoms such as N, 0 or S could coordinate the metal and suppress the catalytic activity. Nevertheless, some interesting early examples of transition-metal-catalyzed syntheses of heterocyclic compounds have been reported and these have been reviewed by C. W. Bird [2] . More recently the incorporation of CO , which enables esters and lactones 2 to be synthesized from olefinic starting materials, has begun to attract attention (see, for example, ref. [3]). The dominant role of palladium as the catalyst for the formation of O-containing heterocycles has been suggested to be associated with the relatively low strength of the Pd-O bond. Among the first examples of a nitrogen-containing heterocycle to be formed by homogeneous catalysis is the triazine shown in Equation 1 which is the product of the trimerization of benzonitrile in the presence of iron penta carbonyl or Raney nickel [4] .

The Design And Development Of New Transition Metal Catalyzed Serial And Multi Component Cycloadditions
Author: Gabriel Grant Gamber
Publisher:
Release Date: 2004
Pages: 470
ISBN:
Available Language: English, Spanish, And French
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Index Volume Category 3
Author: C J Drayton
Publisher: Georg Thieme Verlag
Release Date: 2013-12-11
Pages: 1000
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.//The content of this e-book was originally published in May 2008.

Applications Of Transition Metal Catalysis In Drug Discovery And Development
Author: Matthew L. Crawley
Publisher: John Wiley & Sons
Release Date: 2012-05-14
Pages: 376
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book focuses on the drug discovery and developmentapplications of transition metal catalyzed processes, which canefficiently create preclinical and clinical drug candidates as wellas marketed drugs. The authors pay particular attention tothe challenges of transitioning academically-developed reactionsinto scalable industrial processes. Additionally, the book lays thegroundwork for how continued development of transition metalcatalyzed processes can deliver new drug candidates. This workprovides a unique perspective on the applications of transitionmetal catalysis in drug discovery and development – it is aguide, a historical prospective, a practical compendium, and asource of future direction for the field.

Transition Metal Catalysis In Macromolecular Design
Author: Lisa Saunders Boffa
Publisher: Amer Chemical Society
Release Date: 2000
Pages: 299
ISBN:
Available Language: English, Spanish, And French
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Metal-mediated polymerization is fast becoming an essential tool for the fine control of macromolecular architecture. Advanced Catalysis demonstrates how the field of transition metal-catalyzed polymer syntheses has moved beyond the simple use of single-site catalysts to new applications and "advanced" techniques of architectural control. This book defines and presents "next generation" techniques and trends for polymer architecture control for an immediate grasp on the future of this exciting field.

Progress In Inorganic Chemistry
Author: Kenneth D. Karlin
Publisher: John Wiley & Sons
Release Date: 2014-07-22
Pages: 592
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This series provides inorganic chemists and materials scientistswith a forum for critical, authoritative evaluations of advances inevery area of the discipline. Volume 59 continues to report recentadvances with a significant, up-to-date selection of contributionsby internationally-recognized researchers. The chapters of this volume are devoted to the followingtopics: • Iron Catalysis in Synthetic Chemistry • A New Paradigm for Photodynamic Therapy Drug Design:Multifunctional, Supramolecular DNA Photomodification AgentsFeaturing Ru(II)/Os(II) Light Absorbers Coupled to Pt(II) orRh(III) Bioactive Sites • Selective Binding of Zn2+ Complexes to Non-CanonicalThymine or Uracil in DNA or RNA. • Progress Toward the Electrocatalytic Production ofLiquid Fuels from Carbon Dioxide • Monomeric Dinitrosyl Iron Complexes: Synthesis andReactivity • Interactions of Nitrosoalkanes/arenes, Nitrosamines,Nitrosothiols, and Alkyl Nitrites with Metals • Aminopyridine Iron and Manganese Complexes asMolecular Catalysts for Challenging Oxidative Transformations

Transition Metal Catalysis In Aerobic Alcohol Oxidation
Author: Francesca Cardona
Publisher: Royal Society of Chemistry
Release Date: 2014-10-21
Pages: 280
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The oxidation of primary and secondary alcohols to the corresponding carbonyl compounds is of fundamental importance in organic synthesis, due to the wide use of these products as precursors and intermediates for many drugs, vitamins and fragrances. However, traditional oxidants are often toxic and release considerable amounts of by-products. As an alternative, oxygen is among the cheaper and less polluting stoichiometric oxidants, and the implementation of a transition metal-based catalyst in combination with oxygen represents an emerging alternative to the traditional procedures. This book aims to give an overview of the aerobic oxidation of alcohols catalyzed by transition metals, and covers the most important advances in the last fifteen years. Following an introductory chapter on homogeneous-, heterogeneous- and nano-catalysis, use of copper, ruthenium, palladium, gold, vanadium and iron are discussed in turn. The book concludes with a useful overview that includes representative experimental procedures. This book will provide a valuable reference to organic chemists and green chemists in academia and industry.

Heterocyclic Chemistry
Author: John A. Joule
Publisher: John Wiley & Sons
Release Date: 2013-05-28
Pages: 720
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

Organometallic Chemistry
Author: Edward W. Abel
Publisher: Royal Society of Chemistry
Release Date: 1987
Pages: 532
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This Specialist Periodical Report aims to reflect the growing interest in the potential of organometallic chemistry.

Index Volume Category 4
Author: Colin J. Drayton
Publisher: Georg Thieme Verlag
Release Date: 2013-12-11
Pages: 1288
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.// The content of this e-book was originally published in December 2008.

Ruthenium Catalysis For Atom Economy
Author: Michael Thomas Rudd
Publisher:
Release Date: 2004
Pages: 1274
ISBN:
Available Language: English, Spanish, And French
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C H Activation
Author: Jin-Quan Yu
Publisher: Springer
Release Date: 2010-06-16
Pages: 380
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Table of Contents - Synthesis in the Key of Catellani: Norbornene-Mediated ortho C–H Functionalization - Mechanistic Considerations in the Development and Use of Azine, Diazine and Azole N-Oxides in Palladium-Catalyzed Direct Arylation - Palladium and Copper Catalysis in Regioselective, Intermolecular Coupling of C–H and C–Hal Bonds - Pd-Catalyzed C–H Bond Functionalization on the Indole and Pyrrole Nucleus - Remote C–H Activation via Through-Space Palladium and Rhodium Migrations - Palladium-Catalyzed Aryl–Aryl Bond Formation Through Double C–H Activation - Palladium-Catalyzed Allylic C–H Bond Functionalization of Olefins - Ruthenium-Catalyzed Direct Arylations Through C–H Bond Cleavages - Rhodium-Catalyzed C–H Bond Arylationof Arenes - Cross-Dehydrogenative Coupling Reactions of sp3-Hybridized C–H Bonds - Functionalization of Carbon–Hydrogen Bonds Through Transition Metal Carbenoid Insertion - Metal-Catalyzed Oxidations of C–H to C–N Bonds

Selectivity Control Elements For Transition Metal Catalyzed Cycloaddition Reactions
Author: Michael Charles Matelich
Publisher:
Release Date: 1991
Pages: 1012
ISBN:
Available Language: English, Spanish, And French
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Science Of Synthesis  Houben Weyl Methods Of Molecular Transformations Vol  37
Author:
Publisher: Georg Thieme Verlag
Release Date: 2014-05-14
Pages: 992
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.// The content of this e-book was originally published in May 2008.

Science Of Synthesis  Houben Weyl Methods Of Molecular Transformations Vol  47a
Author: Armin de Meijere
Publisher: Georg Thieme Verlag
Release Date: 2014-05-14
Pages: 632
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.// The content of this e-book was originally published in November 2009.