strategies to modify the drug release from pharmaceutical systems

Strategies To Modify The Drug Release From Pharmaceutical Systems
Author: Marcos Luciano Bruschi
Publisher: Woodhead Publishing
Release Date: 2015-06-16
Pages: 208
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed. Addresses the principles, systems, applications and advances in the field of drug delivery Highlights the mathematical and physicochemical principles related to strategies Discusses drug release and its possible modifications

Release And Bioavailability Of Nanoencapsulated Food Ingredients
Author:
Publisher: Academic Press
Release Date: 2020-06-02
Pages: 508
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Release and Bioavailability of Nanoencapsulated Food Ingredients, volume five in the Nanoencapsulation in the Food Industry series, reviews different release mechanisms of nanoencapsulated food ingredients. The book discusses mathematical and intelligent modeling of the release of bioactive agents from nano-vehicles to better understand their release mechanisms, while also covering different approaches for studying the release profile of these ingredients (such as in-vitro and in-vivo assays). Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical and pharmaceutical ingredients, this title will be of great value to those engaged in various fields of nanoencapsulation. Thoroughly explores the different release mechanisms of nanoencapsulated food ingredients Examines the release of bioactive ingredients by in vitro and in vivo systems Discusses different approaches for modeling the release data of nanoencapsulated ingredients

Basic Fundamentals Of Drug Delivery
Author:
Publisher: Academic Press
Release Date: 2018-11-30
Pages: 810
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation Contains extensive references and further reading for course and self-study

Biomaterials And Implant Biocompatibility
Author: Anişoara Cîmpean
Publisher: MDPI
Release Date: 2020-03-10
Pages: 420
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The scientific advances in life sciences and engineering are constantly challenging, expanding, and redefining concepts related to the biocompatibility and safety of medical devices. New biomaterials, new products, and new testing regimes are being introduced to scientific research practices. In order to provide clinically predictive results and to ensure a high benefit–risk ratio for patients, we need to optimize material and implant characteristics, and to adapt performance and safety evaluation practices for these innovative medical devices. Various characteristics related to materials and implant development such as raw materials composition, implant surface morphology, design, geometry, porosity, and mechanical properties need to be thoroughly characterized before evaluating the biological performance of implants. Furthermore, with the increase of regulatory demands, biological evaluation needs to ensure appropriate models and methods for each implant development stage. This book is a result of the Special Issue of Materials on "Biomaterials and Implant Biocompatibility”, which focused on the recent progress in development, material testing, and the biocompatibility and bioactivity evaluation of various materials including, but not limited to, bioceramics, biopolymers, biometals, composite materials, biomimetic materials, hybrid biomaterials, and drug/device combinations for implants and prostheses with medical applications spanning from soft to hard tissue regeneration. The book covers aspects ranging from investigations into material characterization to in vitro and in vivo testing for the assessment of biological performance of advanced, novel biomaterials and implants.

Nanotechnology For Oral Drug Delivery
Author: João Pedro Martins
Publisher: Academic Press
Release Date: 2020-07-30
Pages: 534
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies. Highlights the relevance of oral drug delivery in the clinical setting Covers the most recent advances in the field of nanotechnology for oral drug delivery Provides the scientific community with data that can facilitate and guide their research

Future Strategies For Drug Delivery With Particulate Systems
Author: Julia E. Diederichs
Publisher:
Release Date: 1998
Pages: 194
ISBN:
Available Language: English, Spanish, And French
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Surface Modification Of Nanoparticles For Targeted Drug Delivery
Author: Yashwant V Pathak
Publisher: Springer
Release Date: 2019-03-11
Pages: 499
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Issues In Pharmacology  Pharmacy  Drug Research  And Drug Innovation  2011 Edition
Author:
Publisher: ScholarlyEditions
Release Date: 2012-01-09
Pages: 4229
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation. The editors have built Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Dissertation Abstracts International
Author:
Publisher:
Release Date: 2008
Pages:
ISBN:
Available Language: English, Spanish, And French
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Polymers For The Medical Industry
Author:
Publisher: iSmithers Rapra Publishing
Release Date: 2001-12-31
Pages: 128
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Particulate Technology For Delivery Of Therapeutics
Author: Sougata Jana
Publisher: Springer
Release Date: 2017-10-09
Pages: 451
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The book focuses on novel particulate technologies for the purpose of drug delivery to humans. Nowadays, macro and nano-scale particles are being investigated for targeted delivery of small and large biological macromolecules. The targeting of drugs can minimize the dosage regimen and reduces dose related potential toxicity of drug molecules, which in turn lead to increased potential compliance. Various types of organic, inorganic and polymer particles are currently being investigated. These are attracting the attention of the research workers in the field of drug delivery science and technology. This book covers polymersomes, inorganic- organic composites, gold nanoparticles biopolymer and synthetic polymer particles etc.All aspects of drug delivery in relation to each technology have been described including these advances, Easy to read and understand the content of each chapter Rich in up-to-date information regarding their application.

Topics In Pharmaceutical Sciences  1987
Author: Douwe D. Breimer
Publisher: Elsevier Science Limited
Release Date: 1987
Pages: 529
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The book contains the 38 invited papers presented in 11 symposia at the 47th International Congress of Pharmaceutical Sciences of the International Pharmaceutical Federation (F.I.P.), held in Amsterdam, The Netherlands, 31 August - 4 September 1987. An up-to-date and informative volume - in principle of interest to all those dealing with drugs - with emphasis on the pharmaceutical aspects of drug research. It is particularly directed to pharmaceutical scientists engaged in university departments, in industry and in hospitals and furthermore to those involved in drug research, development, control, regulation and application.

NSAIDS  Design And Development Of Innovative Oral Delivery Systems
Author: Giulia Auriemma
Publisher:
Release Date: 2017
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Recently, different technologies have been used to transform active pharmaceutical ingredients (APIs) into new dosage forms. Engineered drug delivery systems may modify biopharmaceutical properties of the API achieving either immediate or delayed release according to specific therapeutic needs. Particularly, preprogrammed release of oral formulations delivering the drug at expected times may be useful in chronotherapy of early morning pathologies. The conventional approach when dealing with such diseases is to administer NSAIDs two to three times daily. This approach does not allow to fit drug release with symptoms onset resulting in inefficient therapy and poor patient compliance. NSAIDs may be very effective if administered at least 4-6 h before the pain reaches its peak in the early morning. The solution could be to design delayed drug delivery systems allowing one administration before going to sleep acting in the early morning. This chapter highlights new approaches in developing controlled delivery systems of NSAIDs potentially useful to treat both acute and chronic inflammation. The chapter illustrates the versatility of laminar jet break-up technology (prilling) to produce gel beads able to control rate and time of drug delivery. A special focus will be on particle-engineering strategies, id est, prilling and prilling technique in tandem with microwave or supercritical fluid-assisted drying.

Nanoparticles For Brain Drug Delivery
Author: Taylor & Francis Group
Publisher:
Release Date: 2021-01-21
Pages: 350
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

In an era wherein nanotechnology has sparked a huge research interest, brain drug delivery is not an exception. Aiming at fighting several central nervous system (CNS) conditions, tailored nanoparticles open new avenues to address several challenges in the fields of drug delivery and brain targeting. This book gathers contributions from experts in different, complementary fields, having in common their interest in developing new strategies for brain delivery based on nanotechnologies. The book encompasses general aspects pertaining to fundamental development, including tripartite in silico-in vitro-in vivo approaches. It also covers a diversity of nanomedicines applied in treatment and/or diagnosis and monitoring of CNS disorders. Aspects concerning their translation from the bench to clinical practice are also seamlessly discussed. This book will inspire readers to discover possible approaches to holistically delivering drugs into the brain. Edited by Carla Vitorino, Andreia Jorge and Alberto Pais, this book will appeal to anyone involved in nanomedicine, pharmaceutics, neurological and cancer therapies, drug delivery research and computational and regulatory sciences.

Index To Theses With Abstracts Accepted For Higher Degrees By The Universities Of Great Britain And Ireland And The Council For National Academic Awards
Author:
Publisher:
Release Date: 2009
Pages:
ISBN:
Available Language: English, Spanish, And French
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Chemistry And Industry
Author:
Publisher:
Release Date: 2000
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Pharmacology And Therapeutics For Dentistry   E Book
Author: John A. Yagiela
Publisher: Elsevier Health Sciences
Release Date: 2010-03-19
Pages: 960
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Use your knowledge of pharmacology to enhance oral care! Pharmacology and Therapeutics for Dentistry, 6th Edition describes how to evaluate a patient’s health and optimize dental treatment by factoring in the drugs they take. It explores the basic fundamentals of pharmacology, special topics such as pain control, fear and anxiety, and oral complications of cancer therapy, and most importantly, the actions of specific drug groups on the human body. Whether you’re concerned about the drugs a patient is already taking or the drugs you prescribe for treatment, this book helps you reduce risk and provide effective dental care. An emphasis on the dental applications of pharmacology relates drugs to dental considerations in clinical practice. Dental aspects of many drug classes are expanded to include antibiotics, analgesics, and anesthetics. The Alternative Medicine in Dentistry chapter discusses chemicals used as alternative medicines and assesses their potential benefits and risks. The Nonopioid Analgesics chapter groups together non-opioid analgesics, nonsterioidal anti-inflammatory drugs, and antirheumatic and antigout drugs, making these easier to locate and study. Coverage of the endocrine system includes four separate chapters for the most comprehensive coverage. Drug Interactions in Clinical Dentistry appendix lists potential interactions between drugs a patient is taking for nondental conditions and drugs that may be used or prescribed during dental treatment, including effects and recommendations. Glossary of Abbreviations appendix includes the most common abbreviations used for drugs or conditions. New Pharmacogenetics and Pharmacogenomics chapter covers the effects of genetic traits of patients on their responses to drugs. A NEW introductory section offers tips for the study of dental pharmacology and relates pharmacology to dental considerations. An updated discussion of drug-drug interactions covers the harmful effects of mixing medications. Coverage of adverse effects and mechanisms of COX-2 inhibitors, antibiotic prophylaxis, and antiplaque agents explains the dental risks relating to common drug treatments.

Drug Delivery Systems
Author: Vasant V. Ranade
Publisher: CRC Press
Release Date: 1996
Pages: 364
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book contains - chapter focusing on novel technologies and their global outlook; coverage of electronically controlled drug delivery; macrocapsules and nanoparticles in drug targeting; drug nanocrystals and other new delivery systems; updated information on liposomes as carriers. The author provides a global perspective on current and future advances and market opportunities.

Handbook Of Diet  Nutrition And The Skin
Author: Victor R. Preedy
Publisher: Springer
Release Date: 2012-05-23
Pages: 487
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Studies have clearly shown that optimal diet and nutrition can prevent skin disease. Moreover, novel nutritional components have been used experimentally to treat skin conditions. However, the clinical application of these nutrients awaits confirmation. It is thus up to health care professionals to present new knowledge in order to provide advice or treatments for skin problems. This handbook provides, in a single volume, comprehensive coverage of the relation between skin and diet and nutrition in its broadest sense. The Handbook of diet, nutrition and the skin consists of sections on general aspects of skin, nutrition and diet, micronutrients, nutraceuticals, cancer and specific skin conditions. Unique features of each chapter in this volume include relevant and useful 'key facts' which highlight interesting or important findings of the specific subjects and 'summary points' that are designed to abstract each chapter in take home messages. This handbook will be of interest to a wide range of readers, such as dermatologists, doctors, nurses and those interested in, or working within the area of skin health. This will of course also include nutritionists and dieticians, dermatologists, cosmetic scientists, health workers and practitioners, college and university lecturers and undergraduate and graduate students.

South African Journal Of Science
Author:
Publisher:
Release Date: 2003
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS: