regenerative engineering of musculoskeletal tissues and interfaces

Regenerative Engineering Of Musculoskeletal Tissues And Interfaces
Author: Syam Nukavarapu
Publisher: Woodhead Publishing
Release Date: 2015-04-24
Pages: 462
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces Presents recent developments, fundamentals and progress in the field of engineering tissues Reviews progress and advances in tissue vascularization and innervation

Regenerative Engineering
Author: Cato T. Laurencin
Publisher: CRC Press
Release Date: 2013-06-20
Pages: 435
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Distinct from tissue engineering, which focuses primarily on the repair of tissues, regenerative engineering focuses on the regeneration of tissues: creating living, functional tissue that has the ability to replace organs that are dysfunctional. The challenge of working in an area like regenerative engineering lies, in part, in the breadth of information required to truly appreciate and begin to think about this field. Regenerative Engineering introduces the field through the presentation of fundamental concepts of cell biology, stem cell science, materials science, and cell-material interactions. It also focuses on specific organ and tissue types and presents up-to-date examples of ongoing work, often in the context of a specific clinical need. Regenerative medicine focuses on the biological aspects of tissue regeneration via stem cells, factors, and cytokines, while tissue engineering focuses on the integration of materials science and life sciences. This book integrates these two areas, presenting each concept in the framework of regenerative engineering. Features: Covers a number of cutting-edge topics related to regenerative medicine and tissue engineering Includes an introductory chapter on materials science Features a number of the contributors who are world-class researchers, one of whom is Dr. Anthony Atala, whose work dealing with organ regenerative engineering was featured on Sixty Minutes Incorporates problem-based learning throughout the text, which is not hypothetical but based on actual biological, engineering, or clinical scenarios Combining science, engineering and medicine, Regenerative Engineering incorporates all of the essential elements needed for further advancement in this field. The book explores the development and examination of vital organs and tissue types and addresses concerns as it relates to the regenerative engineering of various organ tissues, vascular tissues, bone, ligament, neural tissue, and the interfaces between tissues.

Bio Instructive Scaffolds For Musculoskeletal Tissue Engineering And Regenerative Medicine
Author: Justin Brown
Publisher: Academic Press
Release Date: 2016-11-03
Pages: 252
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine Focuses on how materials of structures can be designed to be resistant while promoting viable grafts Contains major tissue types that are covered with a strategy for each material and structure

Nanoengineering In Musculoskeletal Regeneration
Author: Mehdi Razavi
Publisher: Academic Press
Release Date: 2020-08
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation. Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of therapeutic pipeline from biomedical discovery to clinical implementation, improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus and bone. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in the musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.

Nanocomposites For Musculoskeletal Tissue Regeneration
Author: Huinan Liu
Publisher: Woodhead Publishing
Release Date: 2016-02-23
Pages: 406
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass

Polymeric Biomaterials For Tissue Regeneration
Author: Changyou Gao
Publisher: Springer
Release Date: 2016-10-08
Pages: 386
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book reviews state-of-the-art of polymeric biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physicochemical property modulation, as well as their influence on adhesion and the performance of biomolecules, cells and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies.

Racing For The Surface
Author: Bingyun Li
Publisher: Springer Nature
Release Date: 2020-02-28
Pages: 809
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.

Nanotechnology And Regenerative Engineering
Author: Cato T. Laurencin
Publisher: CRC Press
Release Date: 2014-10-28
Pages: 476
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Nanotechnology and regenerative engineering have emerged to the forefront as the most versatile and innovative technologies to foster novel therapeutic techniques and strategies of the twenty-first century. The first edition of Nanotechnology and Tissue Engineering: The Scaffold was the first comprehensive source to explain the developments in nanostructured biomaterials for tissue engineering, the relevance of nanostructured materials in tissue regeneration, and the current applications of nanostructured scaffolds for engineering various tissues. This fully revised second edition, renamed Nanotechnology and Regenerative Engineering: The Scaffold, provides a thorough update to the existing material, bringing together these two unique areas to give a perspective of the emerging therapeutic strategies for a wide audience. New coverage includes: Updated discussion of the importance of scaffolds in tissue engineering Exploration of cellular interactions at the nanoscale Complete range of fabrication processes capable of developing nanostructured scaffolds for regenerative engineering Applications of nanostructured scaffolds for neural, skin, cardiovascular, and musculoskeletal regenerative engineering FDA approval process of nanostructure scaffolds Products based on nanostructured scaffolds Due to the unique and tissue-mimic properties of the nanostructured scaffolds, the past five years have seen a tremendous growth in nanostructured materials for biological applications. The revised work presents the current state-of-the-art developments in nanostructured scaffolds for regenerative engineering.

Nanotechnology In Tissue Engineering And Regenerative Medicine
Author: Ketul Popat
Publisher: CRC Press
Release Date: 2010-11-22
Pages: 302
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Although nanotechnology applied to medicine has a potentially huge impact on drug delivery and tissue engineering, significant challenges need to be resolved before clinically viable nanomedicine or nanobiomedicine therapies will be available. Skillfully edited, with contributions from an expert panel of researchers, Nanotechnology in Tissue Engineering and Regenerative Medicine discusses the use of nanotechnology for medical applications with a focus on its use for drug delivery and tissue engineering. It sheds light on the challenges facing the field and examines cutting-edge research that may provide solutions. Topics covered include: Patterning of biomimetic substrates with AFM lithography, primarily focusing on DPN Nanotemplating polymer melts Nanotechnology-based approaches in the treatment of injuries to tendons and ligaments Progress in the use of electrospinning processing techniques for fabricating nanofiber scaffolds for neural applications Nanotopography techniques for tissue-engineered scaffolds and the effects of nanotopography on cells and tissues Vertically aligned TiO2 nanotube surface structuring for optimization of Ti implants utilizing nanotechnology Applications originating from the harmony of nanotechnology to biological systems, especially for the regeneration in the nervous system Current understanding of the mechanisms by which cells sense nano-scale structure at the molecular level and how this understanding can be useful in developing novel antifouling materials While there are books available on tissue engineering and nanotechnology and others about regenerative medicine, most do not comprehensively cover applications of nanotechnology to both these areas. Focusing chiefly on drug delivery, tissue engineering, and regenerative medicine, the book uses an application-based approach to relate laboratory-based research to the development of technologies that can be readily adaptable to an industrial environment.

Regenerative Strategies For The Treatment Of Knee Joint Disabilities
Author: Joaquim Miguel Oliveira
Publisher: Springer
Release Date: 2016-09-26
Pages: 411
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book presents regenerative strategies for the treatment of knee joint disabilities. The book is composed of four main sections totaling 19 chapters which review the current knowledge on the clinical management and preclinical regenerative strategies. It examines the role of different natural-based biomaterials as scaffolds and implants for addressing different tissue lesions in the knee joint. Section one provides an updated and comprehensive discussion on articular cartilage tissue regeneration. Section two focuses on the important contributions for bone and osteochondral tissue engineering. Section three overview the recent advances on meniscus repair/regeneration strategies. Finally, section four further discusses the current strategies for treatment of ligament lesions. Each chapter is prepared by world know expert on their fields, so we do firmly believe that the proposed book will be a reference in the area of biomaterials for regenerative medicine.

3D Bioprinting In Regenerative Engineering
Author: Ali Khademhosseini
Publisher: CRC Press
Release Date: 2018-04-17
Pages: 385
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book is comprehensive in nature with contributions by leading world experts in 3D bioprinting related to regenerative engineering. It includes history, incorporating the process and methods used in bioprinting. Significant sections will be reserved for the applications of the types of tissues generated by using bioprinting, along with an overview of different technologies used in bioprinting. In addition to equipment, the book also describes the different biomaterials and cells used in these approaches. Overall this is a book that includes both entry-level knowledge and advanced methods and techniques. Applications will emphasize engineering and clinical principles.

Polymers For Regenerative Medicine
Author: Carsten Werner
Publisher: Springer Verlag
Release Date: 2006-07-20
Pages: 227
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Table of contents - T. Freier - Biopolyesters in Tissue Engineering Applications.- C. Werner, T. Pompe, K. Salchert - Modulating Extracellular Matrix at Interfaces of Polymeric Materials.- S. Varghese, J.H. Elisseeff - Hydrogels for Musculoskeletal Tissue Engineering.- X. Zhao, S. Zhang - Self-Assembling Nanopeptides Become a New Type of Biomaterials.- A.J. Garcia - Interfaces to Control Cell-Biomaterial Adhesive Interactions.- C. Fischbach, D.J. Mooney - Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules.

Surfaces And Interfaces For Biomaterials
Author: Pankaj Vadgama
Publisher: CRC Press
Release Date: 2005-06-14
Pages: 802
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Given such problems as rejection, the interface between an implant and its human host is a critical area in biomaterials. Surfaces and Interfaces for Biomaterials summarizes the wealth of research on understanding the surface properties of biomaterials and the way they interact with human tissue. The first part of the book reviews the way biomaterial surfaces form. Part Two then discusses ways of monitoring and characterizing surface structure and behavior. The final two parts of the book look at a range of in vitro and in vivo studies of the complex interactions between biomaterials and the body. Chapters cover such topics as bone and tissue regeneration, the role of interface interactions in biodegradable biomaterials, microbial biofilm formation, vascular tissue engineering and ways of modifying biomaterial surfaces to improve biocompatibility. Surfaces and Interfaces for Biomaterials will be a standard work on how to understand and control surface processes in ensuring biomaterials are used successfully in medicine.

Tissue Engineering Strategies For Fibrocartilage Interface Regeneration
Author: Dovina Qu
Publisher:
Release Date: 2019
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Thus, the studies detailed in this thesis consist of elucidation of key interface characteristics that can inform interface scaffold design, identification of an optimal cell source, and optimization of chemical and physical stimuli for fibrocartilage formation. To guide biomimetic scaffold design, this thesis began with quantitative mapping of the compositional and structural properties of the native ligament-to-bone interface. As both the aligned collagen matrix structure and distinctive mineral distribution pattern across the insertion were shown to be highly conserved over time, an ideal scaffold for fibrocartilage interface regeneration should therefore consist of aligned fibers and must be able to support the formation of both non-mineralized and mineralized fibrocartilage tissues. Additionally, evaluation of ex vivo behavior of insertion fibrochondrocytes cultured on aligned nanofiber scaffolds indicated that an ideal system for fibrocartilage regeneration should also support cell-mediated deposition of both types I and II collagen as well as proteoglycans.

Micro And Nanotechnologies In Engineering Stem Cells And Tissues
Author: Murugan Ramalingam
Publisher: John Wiley & Sons
Release Date: 2013-05-10
Pages: 328
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

A cutting-edge look at the application of micro andnanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stemcells/tissue engineering has seen an explosion of activity inrecent years. This book provides a much-needed overview of theseexciting developments, covering all aspects of micro andnanotechnologies, from the fundamental principles to the latestresearch to applications in regenerative medicine. Written and edited by the top researchers in the field, Microand Nanotechnologies in Engineering Stem Cells and Tissuesdescribes advances in material systems along with currenttechniques available for cell, tissue, and organ studies. Readerswill gain tremendous insight into the state of the art of stemcells and tissue engineering, and learn how to use the technologyin their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissuegrowth Various engineering approaches for stem cell, vascular tissue,and bone regeneration The design and processing of biocompatible polymers and otherbiomaterials Characterization of the interactions between cells andbiomaterials Unrivaled among books of this kind, Micro andNanotechnologies in Engineering Stem Cells and Tissues is theultimate forward-looking reference for researchers in numerousdisciplines, from engineering and materials science to biomedicine,and for anyone wishing to understand the trends in thistransformative field.

Stem Cell Nanoengineering
Author: H. Baharvand
Publisher: John Wiley & Sons
Release Date: 2014-12-30
Pages: 432
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Stem Cell Nanoengineering reviews the applications of nanotechnology in the fields of stem cells, tissue engineering, and regenerative medicine. Topics addressed include various types of stem cells, underlying principles of nanobiotechnology, the making of nano-scaffolds, nano tissue engineering, applications of nanotechnology in stem cell tracking and molecular imaging, nano-devices, as well as stem cell nano-engineering from bench to bedside. Written by renowned experts in their respective fields, chapters describe and explore a wide variety of topics in stem cell nanoengineering, making the book a valuable resource for both researchers and clinicians in biomedical and bioengineering fields.

Interface Oral Health Science 2007
Author: M. Watanabe
Publisher: Springer Science & Business Media
Release Date: 2008-08-26
Pages: 385
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Since 2002, the Tohoku University Graduate School of Dentistry has proposed “Interface Oral Health Science” as a major theme for next-generation dental research. That theme is based on the innovative concept that healthy oral function is provided by biological and biomechanical harmony among three systems: (1) oral tissues including the teeth, mucosa, bones, and muscles (host); (2) parasitic microorganisms of the oral cavity (parasites); and (3) biomaterials. The concept posits that oral diseases such as dental caries, periodontal disease, and tempo- mandibular disorders should be interpreted as interface diseases that result from disruption of the intact interfaces among these systems. The uniqueness of this concept rests on the fact that it not only encompasses the entire ? eld of dentistry and dental care, but also expands the common ground shared with many other ? elds, including medicine, pharmaceutical science, agriculture, material science, and engineering. Our Graduate School of Dentistry aims to promote advances in dental research and to activate interdisciplinary research with related ? elds by putting interface oral health science into practice. On this basis we organized the First International Symposium for Interface Oral Health in February 2005, with productive discussions stimulated by two special lectures, three symposia, and poster presentations. A monograph titled Interface Oral Health Science that s- marized the contents of the symposium was published in the autumn of 2005 (International Congress Series 1284, Elsevier, Amsterdam). The Second International Symposium was the most recent.

Functional Tissue Engineering
Author: Farshid Guilak
Publisher: Springer Science & Business Media
Release Date: 2006-04-20
Pages: 426
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

-Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology

Osteochondral Tissue Engineering
Author: J. Miguel Oliveira
Publisher: Springer
Release Date: 2018-04-24
Pages: 438
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book reviews the most recent developments in the field of osteochondral tissue engineering (OCTE) and presents challenges and strategies being developed that face not only bone and cartilage regeneration, but also establish osteochondral interface formation in order to translate it into a clinical setting. Topics include nanotechnology approaches and biomaterials advances in osteochondral engineering, advanced processing methodology, as well as scaffolding and surface engineering strategies in OCTE. Hydrogel systems for osteochondral applications are also detailed thoroughly. Osteochondral Tissue Engineering: Nanotechnology, Scaffolding-Related Developments and Translation is an ideal book for biomedical engineering students and a wide range of established researchers and professionals working in the orthopedic field.

Tissue Engineering
Author: John P. Fisher
Publisher: CRC Press
Release Date: 2012-12-11
Pages: 771
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the fi