polysaccharide carriers for drug delivery

Polysaccharide Carriers For Drug Delivery
Author: Sabyasachi Maiti
Publisher: Woodhead Publishing
Release Date: 2019-06-14
Pages: 802
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Polysaccharide Carriers for Drug Delivery presents the latest information on the selection of safe materials. Due to reported safety profiles on polysaccharides; they have been the natural choice for investigation. A wide variety of drug delivery and biomedical systems have been studied, however, the related information either concept-wise or application-oriented is scattered, therefore becoming difficult for readers and researchers to digest in a concise manner. This gathering of information will help readers easily comprehend the subject matter. Focuses on biopolysaccharide-based, distinct approaches for drug delivery applications Illustrates new concepts and highlights future scope for clinical development Provides comprehensive, up-to-date information on different aspects of drug delivery technology

Alginates In Drug Delivery
Author: Amit Kumar Nayak
Publisher: Academic Press
Release Date: 2020-07-23
Pages: 434
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field. This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. Provides a single source on the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields Includes high quality illustrations, along with practical examples and research case studies Contains contributions by global leaders and experts from academia, industry and regulatory agencies who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields

Advanced Biopolymeric Systems For Drug Delivery
Author:
Publisher: Springer Nature
Release Date: 2020
Pages: 386
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book discusses the recent innovations in the development of various advanced biopolymeric systems, including gels, in situ gels, hydrogels, interpenetrating polymer networks (IPNs), polyelectrolyte complexes (PECs), graft co-polymers, stimuli-responsive polymers, polymeric nanoparticles, nanocomposites, polymeric micelles, dendrimers, liposomes and scaffolds. It also examines their applications in drug delivery.

Polysaccharides In Advanced Drug Delivery
Author: Akhilesh Vikram Singh
Publisher: CRC Press
Release Date: 2020-03-24
Pages: 198
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book contains selective chapters from eminent experts working in the interdisciplinary arena of material science and its use in drug delivery. From their recent research experience, the readers can achieve a wide vision on the new and ongoing potentialities of polysaccharides and its application in the field of advanced drug delivery. This book contains selective polymers that were recently explored in the field of drug delivery such as starch, konjac, chitosan, alginate and other natural polymers originated from sea. It also has one chapter exclusively on nanotechnology that explains multifaceted application of natural polymer in the field of advanced drug delivery. Note: T& F does not sell or distribute the Hardback in India, Pakistan, Nepal, Bhutan, Bangladesh and Sri Lanka.

Biological Activities And Application Of Marine Polysaccharides
Author: Emad Shalaby
Publisher: BoD – Books on Demand
Release Date: 2017-01-11
Pages: 328
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Marine organisms have been under research for the last decades as a source for different active compounds with various biological activities and application in agriculture, pharmacy, medicine, environment, and industries. Marine polysaccharides from these active compounds are used as antibacterial, antiviral, antioxidant, anti-inflammation, bioremediations, etc. During the last three decades, several important factors that control the production of phytoplankton polysaccharides have been identified such as chemical concentrations, temperature, light, etc. The current book includes 14 chapters contributed by experts around the world; the chapters are categorized into three sections: Marine Polysaccharides and Agriculture, Marine Polysaccharides and Biological Activities, and Marine Polysaccharides and Industries.

Polysaccharides For Drug Delivery And Pharmaceutical Applications
Author: R. H. Marchessault
Publisher: Amer Chemical Society
Release Date: 2006
Pages: 365
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Over the last decades we have seen the pharmaceutical industry grow at a tremendous rate. Along with the discoveries of drugs with novel and peculiar properties, the need for novel materials and methods to deliver them energized the field of drug delivery creating new opportunities for material scientists. Among those materials, the pharmaceutical industry has since the beginning relied on cellulose, the most abundant natural polymer on earth. Nowadays, many polysaccharides are used, modified and transformed to serve the pharmaceutical needs either as solubilizers, adhesives, carriers or active substances themselves. This book covers many of the polysaccharides used in the field, their sources, properties, preparation and mechanism of action.

Handbook Of Pharmaceutical Controlled Release Technology
Author: Donald L. Wise
Publisher: CRC Press
Release Date: 2000-08-24
Pages: 902
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems. Contains cutting-edge research on the controlled delivery of biomolecules! Discussing the advantages and limitations of controlled release systems, the Handbook of Pharmaceutical Controlled Release Technology covers oral, transdermal, parenteral, and implantable delivery of drugs discusses modification methods to achieve desired release kinetics highlights constraints of system design for practical clinical application analyzes diffusion equations and mathematical modeling considers environmental acceptance and tissue compatibility of biopolymeric systems for biologically active agents evaluates polymers as drug delivery carriers describes peptide, protein, micro-, and nanoparticulate release systems examines the cost, comfort, disease control, side effects, and patient compliance of numerous delivery systems and devices and more!

Polysaccharide Gold Nanoparticles As Anticancer Drugs Carriers
Author: Mireia Vila Gasull
Publisher:
Release Date: 2011
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Recent advances in nanotechnology have offered a wealth of new opportunities for the design of new therapy of cancer creating new drug delivery systems. It has been possible to produce nanoparticles, in particular polysaccharide-based ones, to allow the site-specific delivery of drugs and to improve the pharmacokinetic profile of numerous compounds. Throughout this work, the system of chitosan (CS)-based nanocarriers produced by coacervation with gum arabic (GA) is presented. The main experiments were focused on the encapsulation of bortezomib (BTZ) and Gold nanoparticles (GoldNP) in the CS/GA system. Completing this work, chemopreventive agents were encapsulated in the same system; catechins (EGCG) and vitamin D; accompanied by Gold nanoparticles too. All the different produced nanoparticles produced were within the size range of 200-400 nm, presenting a low polydispersity index, a positive zeta potential and a spherical shape. The different formulations attained a medium bortezomib encapsulation efficiency of 61%, a EGCG of 40%, a vitamin D of 83% and a Gold nanoparticles encapsulation efficiency of nearly 100%. The encapsulation efficiency was increased for bortezomib, EGCG and vitamin D when the particles were coated with polysorbate 80 which acted as a stabilizing agent. Studies of release for bortezomib and Gold nanoparticles system were carried in water and PBS, showing a biphasic pattern with an initial burst, attributed to the entrapped and surface adsorbed drug, followed by slower release. In water, not all release from nanoparticles was appreciated after long time, besides in PBS it was noted that the nanoparticles were biodegradable. In addition, bortezomib-loaded nanoparticles were tested by in vitro cytotoxic studies. The cytotoxic effect was studied in cancer pancreatic cell line compared to normal pancreatic cell line. They have shown how less concentration of encapsulated bortezomib was needed to have the same effect as free bortezomib in cancer cells. Furthermore, encapsulated bortezomib just inhibited the cell growth as opposed to death of cells produced by free bortezomib, at higher concentrations. According to the results, it is possible to conclude that bortezomib and GoldNP CS/GA nanoparticles is a future alternative to replace the treatment with bortezomib of tumors. Continuing the work with encapsulated EGCG and vitamin D showed also promising results.

Drug Delivery In Oncology
Author: Felix Kratz
Publisher: John Wiley & Sons
Release Date: 2013-09-30
Pages: 1822
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Drug Delivery In Oncology  3 Volume Set
Author: Felix Kratz
Publisher: John Wiley & Sons
Release Date: 2011-11-30
Pages: 1822
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Polysaccharide Based Nanocrystals
Author: Jin Huang
Publisher: John Wiley & Sons
Release Date: 2014-12-03
Pages: 328
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Polysaccharide nanocrystals, an emerging green nanoingredient (nanomaterial) with high crystallinity obtained by acid hydrolysis of biomass-based polysaccharides, are of scientific and economic significance owing to their abundance, biodegradation potential, and fascinating functional performance. This versatile class of materials can be used in nanocomposites such as rubber or polyester, and in functional materials such as drug carriers, bio-inspired mechanically adaptive materials or membranes, to name but a few. This book encompasses the extraction, structure, properties, surface modification, theory, and mechanism of diverse functional systems derived from polysaccharide nanocrystals. This highly sought-after trendy book is currently the only monograph devoted to the most current knowledge pertaining to this exciting subject area. It is ideal for researchers and stakeholders who wish to broaden and deepen their knowledge in the fast-moving and rapidly expanding R&D field of polymeric materials.

Layer By Layer Films For Biomedical Applications
Author: Catherine Picart
Publisher: John Wiley & Sons
Release Date: 2015-02-09
Pages: 592
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The layer-by-layer (LbL) deposition technique is a versatile approach for preparing nanoscale multimaterial films: the fabrication of multicomposite films by the LbL procedure allows the combination of literally hundreds of different materials with nanometer thickness in a single device to obtain novel or superior performance. In the last 15 years the LbL technique has seen considerable developments and has now reached a point where it is beginning to find applications in bioengineering and biomedical engineering. The book gives a thorough overview of applications of the LbL technique in the context of bioengineering and biomedical engineering where the last years have witnessed tremendous progress. The first part familiarizes the reader with the specifics of cell-film interactions that need to be taken into account for successful application of the LbL method in biological environments. The second part focuses on LbL-derived small drug delivery systems and antibacterial agents, and the third part covers nano- and microcapsules as drug carriers and biosensors. The fourth and last part focuses on larger-scale biomedical applications of the LbL method such as engineered tissues and implant coatings.

Engineering Polymer Systems For Improved Drug Delivery
Author: Rebecca A. Bader
Publisher: John Wiley & Sons
Release Date: 2014-01-17
Pages: 496
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

The Complex World Of Polysaccharides
Author: Desiree Nedra Karunaratne
Publisher: BoD – Books on Demand
Release Date: 2012-10-31
Pages: 650
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The complex world of polysaccharides is a compilation of the characteristics of a variety of polysaccharides from plants, animals and microorganisms. The diversity of these polysaccharides arises from the structural variations and the monosaccharide content which is under genetic control. The chemical and physical properties have made them useful in many pharmaceutical, food and industrial applications. These properties of the polysaccharides determine their biological activity and their function in various applications. The role played by polysaccharides in preservation and protection of food, as carriers of nutrients and drugs, their ability to interact with molecules both for efficient delivery as well as improving textures of food colloids and their use as therapeutics are some of the functions discussed.

Multiphase Biomedical Materials
Author: Teiji Tsuruta
Publisher: VSP
Release Date: 1989-12
Pages: 194
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Following many reports that were published in the last two decades on correlations of multiphase structures of the surface of materials with their antithrombogenicity or biocompatibility a research project ''Design of Multiphase Biomedical Materials'' was carried out in Japan between 1982 and 1986. The objective of this research project was to elucidate various aspects of biomedical behaviour of multiphase systems at the interface with living bodies at the molecular, cellular and tissue levels. Multiphase materials studied cover polymers having microphase-separated structures, hydrogels, immobilized enzymes (or cells), ceramics and metallic materials. The research project was carried out by the following subgroups: -- Multiphase biomedical materials with microdomain structures -- Multiphase biomedical materials containing liquid components -- Hybrid-type multiphase biomedical materials with biological components -- Inorganic and metallic multiphase biomedical materials -- Methods for analysis and evaluation of multiphase biomedical materials This book contains the results of the research project in an edited form and aims to provoke a better understanding about various aspects of cell--material interactions in which the multiphase systems play a crucial role.

Modern Trends In Chemistry And Chemical Engineering
Author: A. K. Haghi
Publisher: CRC Press
Release Date: 2011-12-15
Pages: 167
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book covers a collection of topics that reflect the diversity of modern trends in chemistry and chemical engineering. It presents leading-edge research from some of the brightest and most well known scientists from around the world. Contributions range from new methods to novel applications of existing methods to give readers an understanding of the material and/or structural behavior of new and advanced systems. The book offers a broad scope of new research for academics, researchers, and engineering professionals, which has potential for applications in several disciplines of engineering and science. Topics include: Time evolution of the electronegativity and its various scales and the interrelationship between electronegativity and other periodic parameters The starch nanocomposite and nanoparticles and its biomedical applications The lamination of nanofiber at different temperatures Electrospinning of chitosan (CHT) and how it can be improved by the addition of synthetic materials including carbon nanotubes (CNTs) Smart nanofibers based on nylon 6,6/polyethylene glycol blend Nano-biocomposites with chitosan matrix and carbon nanotubes (CNTs) Polypyrrole-coated polyacrylonitrile electrospun nanofibers Semi-empirical AM-1 studies on porphyrin, which include global reactivity parameters, local reactivity parameters, and atomic charge

Natural Polymer Drug Delivery Systems
Author: Saurabh Bhatia
Publisher: Springer
Release Date: 2016-09-23
Pages: 225
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.

Polysaccharide Building Blocks
Author: Youssef Habibi
Publisher: John Wiley & Sons
Release Date: 2012-03-14
Pages: 430
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book is an archival reference for the evolving field ofbiomaterials and their applications in society, focusing on theircomposition, properties, characterization, chemistry andapplications in bioenergy, chemicals, and novel materials andbiomaterials. It has broad appeal due to the recentheightened awareness around bioenergy and biomass as potentialreplacements for petroleum feedstocks. The book isdivided into three parts: cellulose-based biomaterials, chitin andchitosan biomaterials, and hemicelluloses and otherpolysaccharides. Each chapter addresses a separatebiomaterial, discussing its chemical, physical, and biologicalattributes, and hones in on each compound's intrinsictunability for numerous chemicaltransformations. In the current quest for a "green"economy and resources, this book will help inspire scientiststowards novel sources for chemicals, materials,and energy in the years to come.

Advances In Biotechnology Research And Application  2013 Edition
Author:
Publisher: ScholarlyEditions
Release Date: 2013-06-21
Pages: 427
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Advances in Biotechnology Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Bioelectronics. The editors have built Advances in Biotechnology Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioelectronics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Biotechnology Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Effect Of Gel Strength On Drug Release From Swellable Matrices Through Ploymer Erosion
Author: Lan Xiao
Publisher:
Release Date: 2007
Pages: 174
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS: