pharmaceutical applications of dendrimers

Pharmaceutical Applications Of Dendrimers
Author: Abhay Singh Chauhan
Publisher: Elsevier
Release Date: 2019-11-15
Pages: 398
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems Discusses the potential of dendrimers in preformulation and formulation development Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations

Dendrimers For Drug Delivery
Author: Anil K. Sharma
Publisher: CRC Press
Release Date: 2018-07-27
Pages: 426
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.

Polysaccharides In Medicinal And Pharmaceutical Applications
Author: Valentin Popa
Publisher: Smithers Rapra
Release Date: 2011-06-30
Pages: 408
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Polysaccharides in Medicinal and Pharmaceutical Applications presents new and specific aspects in the field of polysaccharides and their derivatives recommended for use in medicine and pharmacy. At the same time the aspects developed in this book will be useful to designing new systems for drugs delivery, immunomodulation, and new materials based on polysaccharides isolated from different sources and their derivatives.

Dendrimer Based Drug Delivery Systems
Author: Yiyun Cheng
Publisher: John Wiley & Sons
Release Date: 2012-05-23
Pages: 534
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The opportunities and challenges of using dendrimers to improvedrug delivery Among pharmaceutical and biomedical researchers, the use ofdendrimers in drug delivery systems has attracted increasinginterest. In particular, researchers have noted that the volume ofa dendrimer increases when it has a positive charge. If thisproperty can be applied effectively, dendrimers have enormouspotential in drug delivery systems, directly supplying medicationto targeted human organs. With contributions from an international team of pioneers andexperts in dendrimer research, this book provides a comprehensiveoverview of the latest research efforts in designing and optimizingdendrimer-based drug delivery systems. The book analyzes keyissues, demonstrating the critical connections that linkfundamental concepts, design, synthesis, analytical methodology,and biological assessment to the practical use of dendrimers indrug delivery applications. Topics covered include: Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields Dendrimer-Based Drug Delivery Systems reflects theauthors' thorough review and analysis of the current literature aswell as their own firsthand experience in the lab. Readers will notonly discover the current state of the science, but also gainvaluable insights into fruitful directions for future research.References at the end of each chapter serve as a gateway to thegrowing body of literature in the field, enabling readers toexplore each individual topic in greater depth. Pharmaceutical and biomedical researchers will find this book aunique and essential guide to the opportunities, issues, andchallenges involved in fully exploiting the potential of dendrimersto improve drug delivery.

Polymeric Biomaterials
Author: Severian Dumitriu
Publisher: CRC Press
Release Date: 2013-01-17
Pages: 820
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Biomaterials have had a major impact on the practice of contemporary medicine and patient care. Growing into a major interdisciplinary effort involving chemists, biologists, engineers, and physicians, biomaterials development has enabled the creation of high-quality devices, implants, and drug carriers with greater biocompatibility and biofunctionality. The fast-paced research and increasing interest in finding new and improved biocompatible or biodegradable polymers has provided a wealth of new information, transforming this edition of Polymeric Biomaterials into a two-volume set. This volume, Polymeric Biomaterials: Medicinal and Pharmaceutical Applications, contains 28 authoritative chapters written by experts from around the world. Contributors cover the following topics: Processing polymeric biomaterials into specific forms that ensure biocompatibility and biodegradability for use in various applications in the medical and pharmaceutical arenas Use of biomaterials to address medical issues such as pulmonary disease, cancer, heart disease, tissue damage, and bone disease Applications including a variety of drug delivery systems, medical devices, anticancer therapies, biological uses for hydrogels, nanotechnology, bioartificial organs, and tissue engineering Completely revised and expanded, this state-of-the-art reference presents recent developments in polymeric biomaterials and the most up-to-date applications of biomaterials in medicine.

Nanotechnologies For Solubilization And Delivery In Foods  Cosmetics And Pharmaceuticals
Author: Nissim Garti
Publisher: DEStech Publications, Inc
Release Date: 2012
Pages: 391
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Beginning with the basics of surfactant chemistry and micellization, this book presents a range of nanotechnology strategies for controlling colloidal and polymeric structures for the solubilization and targeted delivery of food nutrients and pharmaceuticals. The book demonstrates how vehicles for delivering bioactive ingredients through a variety of oral, transdermal, buccal and mucosal routes, can be synthesized by nanolevel manipulation of colloidal systems, proteins, peptides, liquid crystalline phases, organogels and dendrimers. Special attention is given to the modification of mesophases in micellar and liquid crystal systems, which are shown to be productive templates and chemical nanoreactors for uniquely structured nanocarriers. The volume connects micro- and nanolevel modification of emulsion-based and biopolymeric systems, as well as the formation of new nanoparticles, to key properties of absorption, bioavailability and therapeutic effectiveness for dozens of well-known and experimental drugs, food nutrients and antimicrobials. Throughout, a stress is placed on chemical strategies for enhancing the efficiency of drug and nutrient carriers. The information presented in this book is applicable to the design of micro- and nanolevel delivery systems with improved targeting, more efficient controlled release, and superior in vivo penetration into dermal and cellular structures.

Pharmaceutical Applications Of Polymers For Drug Delivery
Author: David Jones
Publisher: iSmithers Rapra Publishing
Release Date: 2004
Pages: 124
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Annotation The review focuses on the use of pharmaceutical polymer for controlled drug delivery applications. Examples of pharmaceutical polymers and the principles of controlled drug delivery are outlined and applications of polymers for controlled drug delivery are described. The field of controlled drug delivery is vast therefore this review aims to provide an overview of the applications of pharmaceutical polymers. The review is accompanied by approximately 250 abstracts taken from papers and books in the Rapra Polymer Library database, to facilitate further reading on this subject.

Biological And Pharmaceutical Applications Of Nanomaterials
Author: Polina Prokopovich
Publisher: CRC Press
Release Date: 2015-06-26
Pages: 444
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Biological and Pharmaceutical Applications of Nanomaterials presents the findings of cutting-edge research activities in the field of nanomaterials, with a particular emphasis on biological and pharmaceutical applications. Divided into four sections—nanomaterials for drug delivery, antimicrobial nanomaterials, nanomaterials in biosensors, and safety of nanomaterials—this book: Covers topics such as stimuli-responsive nanostructured silica matrixes, gold nanoparticles, and liposomes for targeting drug delivery and dental applications Describes the use of nanocarriers and nanoparticles as cancer and peptide therapeutics, the influence of surface characteristics on microbial adhesion, and the latest developments in antimicrobial nanostructured polymers for medical applications Discusses recent advances in nanodiagnostic techniques for infectious agents, chromogenic biosensors for pathogen detection, electrochemical biosensors for detecting DNA damage and genotoxicity, and molecular imaging with quantum dots including surface modifications by polymers for biosensing applications Featuring contributions from field experts and researchers in industry and academia, Biological and Pharmaceutical Applications of Nanomaterials provides state-of-the-art information on nanomaterials and their use in drug delivery, infection control, and biomedicine.

Handbook Of Polymers For Pharmaceutical Technologies  Bioactive And Compatible Synthetic   Hybrid Polymers
Author: Vijay Kumar Thakur
Publisher: John Wiley & Sons
Release Date: 2015-10-22
Pages: 432
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers

Pharmaceutical Nanotechnology
Author: Costas Demetzos
Publisher: Springer
Release Date: 2016-05-11
Pages: 203
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This textbook explains the fundamental aspects of nanotechnology and fills the gap between bio-inspired nanotechnological systems and functionality of living organisms, introducing new insights to their physicochemical, biophysical and thermodynamic behaviour. Addressed to all those involved in recent advances in pharmaceutics, this book is divided in three major parts: Part A refers to the physicochemical and thermodynamics aspects of nanosystems, wherein their biophysical behaviour is correlated with that of the cells of living organisms; Part B refers to the application of nanotechnology in imaging, diagnostics and therapeutics; Part C is focused on issues regarding safety and nanotoxicity of nanosystems, and the regulatory framework that surrounds these. The text promotes the concept that biophysics, thermodynamics and nanotechnology are considered to be emerging tools that, when approached within regulatory boundaries, provide new and integrated knowledge for the production of new medicines.

Multifunctional Pharmaceutical Nanocarriers
Author: Vladimir Torchilin
Publisher: Springer Science & Business Media
Release Date: 2008-03-21
Pages: 474
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The editors have brought together leading experts in multifunctional nanopharmaceuticals to provide cutting edge information; a critical overview of the field; and analysis of current and potential future developments to speed the subject’s rapid development.

Organelle Specific Pharmaceutical Nanotechnology
Author: Volkmar Weissig
Publisher: John Wiley & Sons
Release Date: 2011-03-01
Pages: 608
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book introduces and discusses the latest in biomedical research--Pharmaceutical Nanotechnology applied at the sub-cellular level.

Nanotechnology Applied To Pharmaceutical Technology
Author: Mahendra Rai
Publisher: Springer
Release Date: 2017-11-21
Pages: 386
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Focusing on the application of nanotechnology in pharmaceutical technology the editors seek to integrate the two in order to obtain innovative products and solutions in pharmacology. Interdisciplinary in content it is of interest to those who are involved in the development of nanoproducts including nanotechnologists, microbiologists, biotechnologists pharmacologists and clinicians. Recent studies are presented that include the biosynthesis of nanoparticles focusing on antimicrobials; nanomaterial-based formulations that treat cancer, infections, skin disorders and wounds;nanomaterials in eye diseases and toxicity and safety issues. It demonstrates the crucial role this plays in tackling multi-drug resistant threats.

Dendrimers In Biomedical Applications
Author: Barbara Klajnert
Publisher: Royal Society of Chemistry
Release Date: 2013
Pages: 204
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Dendrimers are important molecules that are currently undergoing investigation for use in a variety of different biomedical applications. This book explores the use of dendrimers for a variety of potential functions, including antiamyloidogenic agents, drug delivery systems, nucleic acid and RNA delivery vectors and to produce hybrid fibre platforms for nantechnology. Following the work of COST action TD0802, the main objective of which is to improve existing therapies and find new drugs based on dendrimers, the book will provide comprehensive coverage of dendrimer applications. Coverage includes modelling and molecular dynamic studies of dendrimers and dendrons, anionic dendrimer polymers, cationic carbosilane dendrimers and self-assembled multivalent dendrimers. Providing clear indications for future research and applications, this text will appeal to chemists, biologists and materials scientists, working in both academia and industry.

Colloids In Drug Delivery
Author: Monzer Fanun
Publisher: CRC Press
Release Date: 2016-04-19
Pages: 652
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles

Bioinspired And Biomimetic Polymer Systems For Drug And Gene Delivery
Author: Zhongwei Gu
Publisher: John Wiley & Sons
Release Date: 2014-12-04
Pages: 360
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompassing small molecule delivery, delivery of therapeutic proteins and gene delivery. The carriers surveyed include polymeric, proteinaceous and lipid systems on the nanoscale, with a focus on their adaptability for different cargoes and target tissues. Thanks to the broad coverage of carriers as well as cargoes discussed, every researcher in the field will find valuable information here.

Tailored Polymer Architectures For Pharmaceutical And Biomedical Applications
Author: Carmen Scholz
Publisher: OUP USA
Release Date: 2014-01
Pages: 376
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Provides detailed information on cutting-edge research in the field of polymer science for biomedical and pharmaceutical applications.

Pharmaceutical Biotechnology
Author: Carlos A. Guzmán
Publisher: Springer Science & Business Media
Release Date: 2010-01-01
Pages: 276
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.

Dendrimers Nanomedicine
Author: NEELESH KUMAR. JAIN MEHRA (KEERTI.)
Publisher: CRC Press
Release Date: 2021-01-27
Pages: 320
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Nanomaterials and nanotechnology are extensively being developed, designed, engineered, tailored, manipulated, explored and investigated for variety of applications in Healthcare, Pharmaceutical, and Biotechnological Research & Innovation area. Nanotechnology based products are rapidly growing and multifunctional engineered nanomaterials (ENM) are emerging as useful tools in biotherapeutics delivery as well. Among various nanomaterials, dendrimers has attracted great attention of scientists and have proved their usefulness and applications in Healthcare, Pharmaceutical, and Biotechnological Research attributed to their unique properties like monodispersity, hyperbranched structure synthesized by controlled chemical reactions, nanometric size and shape. In this book we have covered the nanotechnological aspects, concepts, properties, characterization, application and biofate and regulatory aspects of the dendrimers. The proposed book is edited by two well-known researchers in the area of nanomaterials, including dendrimers, carbon nanotubes, quantum dots etc, based drug delivery applications and contribution of vivid chapters from renowned formulator, researcher and academician across the world with their specialization area of interest in the field of chemistry, biology, pharmacy and nanomedicine.

Engineered Carbohydrate Based Materials For Biomedical Applications
Author: Ravin Narain
Publisher: John Wiley & Sons
Release Date: 2011-03-01
Pages: 416
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.