In the summer of 1953, maverick neurosurgeon William Beecher Scoville performed a groundbreaking operation on an epileptic patient named Henry Molaison. But it was a catastrophic failure, leaving Henry unable to create long-term memories. Scoville's grandson, Luke Dittrich, takes us on an astonishing journey through the history of neuroscience, from the first brain surgeries in ancient Egypt to the New England asylum where his grandfather developed a taste for human experimentation. Dittrich's investigation confronts unsettling family secrets and reveals the dark roots of modern neuroscience, raising troubling questions that echo into the present day.
patient h m
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So much to read, so little time? This brief overview of Patient H.M. tells you what you need to know—before or after you read Luke Dittrich’s book. Crafted and edited with care, Worth Books set the standard for quality and give you the tools you need to be a well-informed reader. This short summary and analysis of Patient H.M.: A Story of Memory, Madness, and Family Secrets includes: Historical context Chapter-by-chapter overviews Profiles of the main characters Detailed timeline of key events Important quotes Fascinating trivia Glossary of terms Supporting material to enhance your understanding of the original work About Patient H.M. by Luke Dittrich: Patient H.M. tells the extraordinary true story of Henry Molaison, a young man who underwent a lobotomy in 1953 in hopes of curing his epilepsy. Instead, he suffered extensive memory loss and would became the most studied patient in the history of neuroscience. Luke Dittrich, whose grandfather performed the surgery, artfully combines family history, medical science, and investigative journalism to create a suspenseful and unsettling narrative on the search to understand the most elusive of scientific research topics: the human memory. The summary and analysis in this ebook are intended to complement your reading experience and bring you closer to a great work of nonfiction.
The cognitive disorders that follow brain damage are an important source of insight into the neural bases of human thought. Although cognitive neuroscience is sometimes equated with cognitive neuroimaging, the patient-based approach to cognitive neuroscience is responsible for most of what we now know about the brain systems underlying perception, attention, memory, language, and higher-order forms of thought including consciousness. This volume brings together state-of-the-art reviews of the patient-based approach to these and other central issues in cognitive neuroscience, written by leading authorities. Part I covers the history, principles, and methods of patient-based neuroscience: lesion method, imaging, computational modeling, and anatomy. Part II covers perception and vision: sensory agnosias, disorders of body perception, attention and neglect, disorders of perception and awareness, and misidentification syndromes. Part III covers language: aphasia, language disorders in children, specific language impairments, developmental dyslexia, acquired reading disorders, and agraphia. Part IV covers memory: amnesia and semantic memory impairments. Part V covers higher cognitive functions: frontal lobes, callosal disconnection (split brain), skilled movement disorders, acalculia, dementia, delirium, and degenerative conditions including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Contributors: Michael P. Alexander, Russell M. Bauer, Kathleen Baynes, D. Frank Benson, H. Branch Coslett, Jeffrey L. Cummings, Tim Curran, Antonio R. Damasio, Hanna Damasio, Ennio De Renzi, Maureen Dennis, Mark D'Esposito, Martha J. Farah, Todd E. Feinberg, Michael S. Gazzaniga, Georg Goldenberg, Jordan Grafman, Kenneth M. Heilman, Diane M. Jacobs, Daniel I. Kaufer, Daniel Y. Kimberg, Maureen W. Lovett, Richard Mayeux, M.-Marsel Mesulam, Bruce L. Miller, Robert D. Nebes, Robert D. Rafal, Marcus E. Raichle, Timothy Rickard, David M. Roane, David J. Roeltgen, Leslie J. Gonzalez Rothi, Eleanor M. Saffran, Daniel L. Schacter, Karin Stromswold, Edward Valenstein, Robert T. Watson, Tricia Zawacki, Stuart Zola.
The study of learning and memory is a central topic in neuroscience and psychology. Many of the basic research findings are directly applicable in the treatment of diseases and aging phenomena, and have found their way into educational theory and praxis. Concise Learning and Memory represents the best 30 chapters from Learning and Memory: A comprehensive reference (Academic Press March 2008), the most comprehensive source of information about learning and memory ever assembled, selected by one of the most respective scientists in the field, John H. Byrne. This concise version provides a truly authoritative collection of overview articles representing fundamental reviews of our knowledge of this central cognitive function of animal brains. It will be an affordable and accessible reference for scientists and students in all areas of neuroscience and psychology. There is no other single-volume reference with such authority and comprehensive coverage and depth currently available. * Represents an authoritative selection of the fundamental chapters from the most comprehensive source of information about learning and memory ever assembled, Learning and Memory - A comprehensive reference (Academic Press Mar 2008) * Representing outstanding scholarship, each chapter is written by a leader in the field and an expert in the topic area * All topics represent the most up to date research * Full color throughout, heavily illustrated * Priced to provide an affordable reference to individuals and workgroups
The Handbook of Cognition provides a definitive synthesis of the most up-to-date and advanced work in cognitive psychology in a single volume. The editors have gathered together a team of world-leading researchers in specialist areas of the field, both traditional and `hot' new areas, to present a benchmark - in terms of theoretical insight and advances in methodology - of the discipline. This book contains a thorough overview of the most significant and current research in cognitive psychology that will serve this academic community like no other volume.
For a period of some fifteen years following completion of my internship training in clinical psychology (1950-1951) at the Washington University School of Medicine and my concurrent successful navigation through that school's neuroanatomy course, clinical work in neuropsychology for me and the psychologists of my generation consisted almost exclusively of trying to help our physician colleagues differentiate patients with neurologic from those with psychiatric disorders. In time, experience led all of us from the several disciplines involved in this enterprise to the conclusion that the crude diag nostic techniques available to us circa 1945-1965 had garnered us little valid information upon which to base such complex, differential diagnostic decisions. It now is gratifying to look back and review the remarkable progress that has occurred in the field of clinical neuropsychology in the four decades since I was a graduate student. In the late 1940s such pioneers as Ward Halstead, Alexander Luria, George Yacorzynski, Hans-Lukas Teuber, and Arthur Benton already were involved in clinical studies that, by the late 1960s, would markedly have improved the quality of clinical practice. However, the only psychological tests that the clinical psychologist of my immediate post-Second World War generation had as aids for the diagnosis of neurologically based conditions involving cognitive deficit were such old standbys as the Wechsler Bellevue, Rorschach, Draw A Person, Bender Gestalt, and Graham Kendall Memory for Designs Test.
Over 5.7 million people in America carry a diagnosis of heart failure, the incidence of which approaches 1 in 100 people over the age of 65. The cost to society is estimated at $29 billion annually and over 1.1 million hospital admissions. For hospitalized heart failure patients, the 30-day readmission rate approaches 25%. As our population ages these numbers are expected to grow. This issue of Cardiology Clinics helps practitioners to manage patients at all ACC/AHA stages of heart failure and addresses key issues that include sudden cardiac death, arrhythmias, acute decompensated heart failure, and heart failure with preserved ejection fraction.
The Cambridge Handbook of Consciousness is the first of its kind in the field, and its appearance marks a unique time in the history of intellectual inquiry on the topic. After decades during which consciousness was considered beyond the scope of legitimate scientific investigation, consciousness re-emerged as a popular focus of research towards the end of the last century, and it has remained so for nearly 20 years. There are now so many different lines of investigation on consciousness that the time has come when the field may finally benefit from a book that pulls them together and, by juxtaposing them, provides a comprehensive survey of this exciting field. An authoritative desk reference, which will also be suitable as an advanced textbook.
It was Oscar Wilde who defined the tragedy of old age by saying that " . . . as soon as you are old enough to know better, you don't know anything at all. " As improvements in the quality of health care bring about longer life, our attention has turned from the prolonging of life to the maintenance of involvement in life. In developed nations, a full 100% increase in the ranks of the elderly has appeared and with the benefits of this prolongation have come new and greater needs of the elderly cohort. Our interest is in those processes that may lead to dementia among the elderly, for in dementia we see a thief that robs victims of their memories and their place in life. This text was conceived and developed from an international con ference on neurodevelopment, aging, and cognition; the purpose of this few days a group of experts in these conference was to bring together for a fields from around the world to generate a dialog on common themes and unresolved problems. Our hope was that by keeping the meeting small and informal, we could break through barriers of terminology unique to the areas of developmental neurobiology, neuroscience, cognitive sci ence, and clinical medicine, and have a meaningful discussion on pro cesses that affect the biological integrity and cognitive performance of the aging nervous system.
Behavioral Neuroscientists study the behavior of animals and humans and the neurobiological and physiological processes that control it. Behavior is the ultimate function of the nervous system, and the study of it is very multidisciplinary. Disorders of behavior in humans touch millions of people’s lives significantly, and it is of paramount importance to understand pathological conditions such as addictions, anxiety, depression, schizophrenia, autism among others, in order to be able to develop new treatment possibilities. Encyclopedia of Behavioral Neuroscience is the first and only multi-volume reference to comprehensively cover the foundation knowledge in the field. This three volume work is edited by world renowned behavioral neuroscientists George F. Koob, The Scripps Research Institute, Michel Le Moal, Université Bordeaux, and Richard F. Thompson, University of Southern California and written by a premier selection of the leading scientists in their respective fields. Each section is edited by a specialist in the relevant area. The important research in all areas of Behavioral Neuroscience is covered in a total of 210 chapters on topics ranging from neuroethology and learning and memory, to behavioral disorders and psychiatric diseases. The only comprehensive Encyclopedia of Behavioral Neuroscience on the market Addresses all recent advances in the field Written and edited by an international group of leading researchers, truly representative of the behavioral neuroscience community Includes many entries on the advances in our knowledge of the neurobiological basis of complex behavioral, psychiatric, and neurological disorders Richly illustrated in full color Extensively cross referenced to serve as the go-to reference for students and researchers alike The online version features full searching, navigation, and linking functionality An essential resource for libraries serving neuroscientists, psychologists, neuropharmacologists, and psychiatrists