modeling and control of infectious diseases in the host

Modeling And Control Of Infectious Diseases In The Host
Author: Esteban A. Hernandez-Vargas
Publisher: Academic Press
Release Date: 2019-02-14
Pages: 256
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R. Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases Presents a theoretic approach to schedule drug treatments

Modeling Infectious Diseases In Humans And Animals
Author: Matt J. Keeling
Publisher: Princeton University Press
Release Date: 2011-09-19
Pages: 408
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control

Infection Control In Home Care And Hospice
Author: Emily Rhinehart
Publisher: Jones & Bartlett Learning
Release Date: 2005-05
Pages: 245
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

An official publication of the Association for Professionals in Infection Control and Epidemiology, Inc. (APIC), the highly successful Infection Control in Home Care and Hospice helps home care providers assess the infection control needs of their organization, and develop home care infection and surveillance programs. The Second Edition has been thoroughly updated and revised with the latest CDC Guidelines on infection control in home care, including Hand Hygiene, Prevention of IV-related Infections, and the 2004 Isolation Guideline.

Modeling To Inform Infectious Disease Control
Author: Niels G. Becker
Publisher: CRC Press
Release Date: 2015-04-28
Pages: 208
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Effectively Assess Intervention Options for Controlling Infectious DiseasesOur experiences with the human immunodeficiency virus (HIV), severe acute respiratory syndrome (SARS), and Ebola virus disease (EVD) remind us of the continuing need to be vigilant against the emergence of new infectious diseases. Mathematical modeling is increasingly used i

Infection Control In Home Care
Author: Emily Rhinehart
Publisher: Jones & Bartlett Learning
Release Date: 1999
Pages: 240
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Provides information to home care and hospice organizations for the prevention, control, and surveillance of infection. Thirteen chapters cover topics including infection control as a health care discipline; the infectious disease process; patient care practices; infection control in home infusion t

Infectious Diseases Of Humans
Author: Roy M. Anderson
Publisher: Oxford University Press
Release Date: 1992-08-27
Pages: 757
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Combines mathematical models with extensive use of epidemiological and other data to achieve a better understanding of the overall dynamics of populations of pathogens or parasites and their human hosts, thus providing an analytic framework for evaluating public health strategies.

Modelling Parasite Transmission And Control
Author: Edwin Michael
Publisher: Springer Science & Business Media
Release Date: 2010-12-31
Pages: 212
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

It is clear that many fascinating problems still remain to be addressed in parasite transmission modelling, from better understanding of transmission processes and natural history of infection to investigating the impact of ecological and spatial scales, climate change, host immunity and social behaviour, parasite-host evolutionary dynamics and parasite community ecology on parasite transmission. This book captures some of the advances made in recent years and provides indications of ways forward for addressing these questions by shedding light on developments in conceptual frameworks and modelling tools as well as the emergence of new data forms for aiding model construction, testing and analysis. Another important advance has been the parallel development of robust computationally-intensive statistical methods to allow model testing and parameterization by aiding the fitting of models to complex data. This is an exciting area of work, which we believe will broaden the scope of mathematical modelling in investigating parasite transmission processes. In particular, we expect this advance will now allow modellers to begin the successful development and analysis of mechanistically-rich models of parasite transmission that will facilitate better integration of the variety of mechanisms increasingly recognized as important in simultaneously affecting transmission, including abiotic processes, trophic and evolutionary interactions, movement in space, and behaviour and even physiology of the individual. We foresee a continuing bright future for using mathematical modelling to clarify parasite transmission dynamics and address problems related to effective parasite control. Ultimately, through this improved application of models to research and management, we expect that parasite control would be an achievable goal bringing benefits to a vast number of our fellow human beings.

Modeling And Dynamics Of Infectious Diseases
Author: Zhien Ma
Publisher: World Scientific
Release Date: 2009
Pages: 343
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book provides a systematic introduction to the fundamental methods and techniques and the frontiers of ? along with many new ideas and results on ? infectious disease modeling, parameter estimation and transmission dynamics. It provides complementary approaches, from deterministic to statistical to network modeling; and it seeks viewpoints of the same issues from different angles, from mathematical modeling to statistical analysis to computer simulations and finally to concrete applications.

In Vivo Models Of HIV Disease And Control
Author: Herman Friedman
Publisher: Springer Science & Business Media
Release Date: 2007-04-27
Pages: 436
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV. Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey, mouse, cat, cow, horse, and other animal viruses are detailed and compared to HIV. Also included are chapters on the history and future of animal models, as well as a chapter on ethical and safety considerations in using animal models for AIDS studies.

Ecology Of Wildlife Host Parasite Interactions
Author: Bryan T. Grenfell
Publisher: Cambridge University Press
Release Date: 1995
Pages: 191
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This new collection of articles, edited by Bryan T. Grenfell includes: Factors affecting the evolution of virulence: nematode parasites of fig wasps; Maintenance of a microparasite infecting several host species in the Seregeti; Wildlife disease and conservation in Hawaii: pathogenicity of avian malaria (Plasmodium relictum) in experimentally infected Iiwi (Vestiaria coccinia).

Antimicrobial Drug Discovery
Author: George Tegos
Publisher: CABI
Release Date: 2012
Pages: 357
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertebrate model hosts and light and nano-based technologies. It is essential reading for researchers and students in microbiology, biotechnology, pharmacology, chemistry and biology as well as medical professionals.

Introduction To Public Health   E Book
Author: Mary Louise Fleming
Publisher: Elsevier Health Sciences
Release Date: 2012-03-09
Pages: 400
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This text introduces students to the core concepts and principles of public health: the nature and scope of public health; its history; an introduction to health determinants and epidemiology; evidence-based practice in public health and understanding public health data plus more.

Mathematics For Life Science And Medicine
Author: Yasuhiro Takeuchi
Publisher: Springer Science & Business Media
Release Date: 2007-01-25
Pages: 228
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The purpose of this volume is to present and discuss the many rich properties of the dynamical systems that appear in life science and medicine. It provides a fascinating survey of the theory of dynamical systems in biology and medicine. Each chapter will serve to introduce students and scholars to the state-of-the-art in an exciting area, to present new results, and to inspire future contributions to mathematical modeling in life science and medicine.

Botrytis  Biology  Pathology And Control
Author: Y. Elad
Publisher: Springer Science & Business Media
Release Date: 2007-10-26
Pages: 428
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The book is the result of intensive work of 43 authors, all of them leading scientists in the Botrytis sciences. Each chapter describes a particular aspect of fungal biology and its impact on disease processes and host response. New technologies have arisen that when applied to long-standing problems or to test new hypotheses have been most rewarding and many of these are covered in this book. The chapters are cross linked so that readers can follow associated material.

Public Health And Infectious Diseases
Author: Jeffrey Griffiths
Publisher: Elsevier
Release Date: 2010-03-09
Pages: 512
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Emerging infectious diseases may be defined as diseases being caused by pathogens only recently recognized to exist. This group of diseases is important globally, and the experience of the last 30 years suggests that new emerging diseases are likely to bedevil us. As the global climate changes, so changes the environment, which can support not only the pathogens, but also their vectors of transmission. This expands the exposure and effects of infectious disease and, therefore, the importance of widespread understanding of the relationship between public health and infectious disease. This work brings together chapters that explain reasons for the emergence of these infectious diseases. These include the ecological context of human interactions with other humans, with animals that may host human pathogens, and with a changing agricultural and industrial environment, increasing resistance to antimicrobials, the ubiquity of global travel, and international commerce. * Features the latest discoveries related to influenza with a newly published article by Davidson Hamer and Jean van Seventer * Provides a listing of rare diseases that have become resurgent or spread their geographic distribution and are re-emergent * Highlights dengue and malaria, as well as agents such as West Nile and other arboviruses that have spread to new continents causing widespread concerns * Includes discussions of climate influencing the spread of infectious disease and political and societal aspects

Controlling Intestinal Helminths While Eliminating Lymphatic Filariasis
Author: L. S. Stephenson
Publisher: Cambridge University Press
Release Date: 2001-11-16
Pages: 182
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Reviews the WHO Global Programme to Eliminate Lymphatic Filariasis and its potential impact for health.

Encyclopedia Of Epidemiology
Author: Sarah Boslaugh
Publisher: SAGE Publications
Release Date: 2007-11-27
Pages: 1240
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The Encyclopedia of Epidemiology presents state-of-the-art information from the field of epidemiology in a less technical and accessible style and format. With more than 600 entries, no single reference provides as comprehensive a resource in as focused and appropriate manner. The entries cover every major facet of epidemiology, from risk ratios to case-control studies to mediating and moderating variables, and much more. Relevant topics from related fields such as biostatistics and health economics are also included.

Towards Host Directed Drug Therapies For Infectious And Non Communicable Diseases
Author: Frank Brombacher
Publisher: Frontiers Media SA
Release Date: 2019-11-25
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Epidemics
Author: Ottar N. Bjørnstad
Publisher: Springer
Release Date: 2018-10-30
Pages: 312
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book is designed to be a practical study in infectious disease dynamics. The book offers an easy to follow implementation and analysis of mathematical epidemiology. The book focuses on recent case studies in order to explore various conceptual, mathematical, and statistical issues. The dynamics of infectious diseases shows a wide diversity of pattern. Some have locally persistent chains-of-transmission, others persist spatially in ‘consumer-resource metapopulations’. Some infections are prevalent among the young, some among the old and some are age-invariant. Temporally, some diseases have little variation in prevalence, some have predictable seasonal shifts and others exhibit violent epidemics that may be regular or irregular in their timing. Models and ‘models-with-data’ have proved invaluable for understanding and predicting this diversity, and thence help improve intervention and control. Using mathematical models to understand infectious disease dynamics has a very rich history in epidemiology. The field has seen broad expansions of theories as well as a surge in real-life application of mathematics to dynamics and control of infectious disease. The chapters of Epidemics: Models and Data using R have been organized in a reasonably logical way: Chapters 1-10 is a mix and match of models, data and statistics pertaining to local disease dynamics; Chapters 11-13 pertains to spatial and spatiotemporal dynamics; Chapter 14 highlights similarities between the dynamics of infectious disease and parasitoid-host dynamics; Finally, Chapters 15 and 16 overview additional statistical methodology useful in studies of infectious disease dynamics. This book can be used as a guide for working with data, models and ‘models-and-data’ to understand epidemics and infectious disease dynamics in space and time.

Vaccinology
Author: Gregg N. Milligan
Publisher: John Wiley & Sons
Release Date: 2014-12-04
Pages: 400
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Vaccinology: An Essential Guide outlines in a clear,practical format the entire vaccine development process, fromconceptualization and basic immunological principles through toclinical testing and licensing of vaccines. With anoutstanding introduction to the history and practice ofvaccinology, it also guides the reader through the basic sciencerelating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economicand geographical issues that drive vaccine development and trials,it also presents vaccine delivery strategies, novel vaccineplatforms (including experimental vaccines and pathogens), antigendevelopment and selection, vaccine modelling, and the developmentof vaccines against emerging pathogens and agents of bioterror.There are also sections devoted to veterinary vaccines andassociated regulatory processes. Vaccinology: An Essential Guide is a perfect tool fordesigned for undergraduate and graduate microbiologists andimmunologists, as well as residents, fellows and trainees ofinfectious disease and vaccinology. It is also suitable for allthose involved in designing and conducting clinical vaccine trials,and is the ideal companion to the larger reference bookVaccinology: Principles and Practice.