medical biosensors for point of care poc applications

Medical Biosensors For Point Of Care  POC  Applications
Author: Roger J Narayan
Publisher: Woodhead Publishing
Release Date: 2016-08-21
Pages: 316
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications Includes contributions from leading international researchers with extensive experience in developing medical biosensors Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care

Advanced Materials And Techniques For Biosensors And Bioanalytical Applications
Author: Pranab Goswami
Publisher: CRC Press
Release Date: 2020-11-04
Pages: 302
ISBN:
Available Language: English, Spanish, And French
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Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research. Advanced Materials and Techniques for Biosensors and Bioanalytical Applications provides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools. Features: • Basic principles on different classes of biosensors, recent advances and applications • Smart materials for biosensors and other rapid, portable detection devices • Metal nanoparticles and nanocrystals for analytical applications • Carbon-based nanoparticles and quantum dots for sensing applications • Nanozymes as potential catalysts for sensing applications • Bioelectrochemiluminescence and photoelectrochemical-based biosensors • Paper electronics and paper-based biosensors • Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology • Biofuel cells as a signal transduction platform • FET-based biosensors, including ISFET and BioFET This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.

Biosensors For Environmental Monitoring
Author: Toonika Rinken
Publisher: BoD – Books on Demand
Release Date: 2019-11-20
Pages: 204
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Real-time and reliable detection of molecular compounds and bacteria is essential in modern environmental monitoring. For rapid analyses, biosensing devices combining high selectivity of biomolecular recognition and sensitivity of modern signal-detection technologies offer a promising platform. Biosensors allow rapid on-site detection of pollutants and provide potential for better understanding of the environmental processes, including the fate and transport of contaminants.This book, including 12 chapters from 37 authors, introduces different biosensor-based technologies applied for environmental analyses.

Drug Targets In Cellular Processes Of Cancer  From Nonclinical To Preclinical Models
Author: Hardeep Singh Tuli
Publisher: Springer Nature
Release Date:
Pages:
ISBN:
Available Language: English, Spanish, And French
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Bioinspired Materials For Medical Applications
Author: Lígia Rodrigues
Publisher: Woodhead Publishing
Release Date: 2016-09-24
Pages: 544
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Bioinspired Materials for Medical Applications examines the inspiration of natural materials and their interpretation as modern biomaterials. With a strong focus on therapeutic and diagnostic applications, the book also examines the development and manipulation of bioinspired materials in regenerative medicine. The first set of chapters is heavily focused on bioinspired solutions for the delivery of drugs and therapeutics that also offer information on the fundamentals of these materials. Chapters in part two concentrate on bioinspired materials for diagnosis applications with a wide coverage of sensor and imaging systems With a broad coverage of the applications of bioinspired biomaterials, this book is a valuable resource for biomaterials researchers, clinicians, and scientists in academia and industry, and all those who wish to broaden their knowledge in the allied field. Explores how materials designed and produced with inspiration from nature can be used to enhance man-made biomaterials and medical devices Brings together the two fields of biomaterials and bioinspired materials Written by a world-class team of research scientists, engineers, and clinicians

Biomedical Technology And Devices  Second Edition
Author: George Zouridakis
Publisher: CRC Press
Release Date: 2013-06-25
Pages: 820
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Biomedical Technology and Devices, Second Edition focuses on the equipment, devices, and techniques used in modern medicine to diagnose, treat, and monitor human illnesses. Gathering together and compiling the latest information available on medical technology, this revised work adds ten new chapters. It starts with the basics, introducing the history of the thermometer and measuring body temperature, before moving on to a medley of devices that are far more complex. This book explores diverse technological functions and procedures including signal processing, auditory systems, magnetic resonance imaging, ultrasonic and emission imaging, image-guided thermal therapy, medical robotics, shape memory alloys, biophotonics, and tissue engineering. Each chapter offers a description of the technique, its technical considerations, and its use according to its applications and relevant body systems. It can be used as a professional resource, as well as a textbook for undergraduate and graduate students.

Nanosensors  Microsensors  And Biosensors And Systems 2007
Author: V. K. Varadan
Publisher: Society of Photo Optical
Release Date: 2007
Pages: 474
ISBN:
Available Language: English, Spanish, And French
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Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.

Point Of Care Testing
Author: Peter Luppa
Publisher: Springer
Release Date: 2018-07-14
Pages: 424
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conven tional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.

Point Of Care Technologies Enabling Next Generation Healthcare Monitoring And Management
Author: Sandeep Kumar Vashist
Publisher: Springer
Release Date: 2019-02-20
Pages: 232
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book describes the emerging point-of-care (POC) technologies that are paving the way to the next generation healthcare monitoring and management. It provides the readers with comprehensive, up-to-date information about the emerging technologies, such as smartphone-based mobile healthcare technologies, smart devices, commercial personalized POC technologies, paper-based immunoassays (IAs), lab-on-a-chip (LOC)-based IAs, and multiplex IAs. The book also provides guided insights into the POC diabetes management software and smart applications, and the statistical determination of various bioanalytical parameters. Additionally, the authors discuss the future trends in POC technologies and personalized and integrated healthcare solutions for chronic diseases, such as diabetes, stress, obesity, and cardiovascular disorders. Each POC technology is described comprehensively and analyzed critically with its characteristic features, bioanalytical principles, applications, advantages, limitations, and future trends. This book would be a very useful resource and teaching aid for professionals working in the field of POC technologies, in vitro diagnostics (IVD), mobile healthcare, Big Data, smart technology, software, smart applications, biomedical engineering, biosensors, personalized healthcare, and other disciplines.

Microfluidics For Biologists
Author: Chandra K. Dixit
Publisher: Springer
Release Date: 2016-10-13
Pages: 252
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This book describes novel microtechnologies and integration strategies for developing a new class of assay systems to retrieve desired health information from patients in real-time. The selection and integration of sensor components and operational parameters for developing point-of-care (POC) are also described in detail. The basics that govern the microfluidic regimen and the techniques and methods currently employed for fabricating microfluidic systems and integrating biosensors are thoroughly covered. This book also describes the application of microfluidics in the field of cell and molecular biology, single cell biology, disease diagnostics, as well as the commercially available systems that have been either introduced or have the potential of being used in research and development. This is an ideal book for aiding biologists in understanding the fundamentals and applications of microfluidics. This book also: Describes the preparatory methods for developing 3-dimensional microfluidic structures and their use for Lab-on-a-Chip design Explains the significance of miniaturization and integration of sensing components to develop wearable sensors for point-of-care (POC) Demonstrates the application of microfluidics to life sciences and analytical chemistry, including disease diagnostics and separations Motivates new ideas related to novel platforms, valving technology, miniaturized transduction methods, and device integration to develop next generation sequencing Discusses future prospects and challenges of the field of microfluidics in the areas of life sciences in general and diagnostics in particular

BioMEMS
Author: Simona Badilescu
Publisher: CRC Press
Release Date: 2011-06-13
Pages: 368
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

As technological advancements widen the scope of applications for biomicroelectromechanical systems (BioMEMS or biomicrosystems), the field continues to have an impact on many aspects of life science operations and functionalities. Because BioMEMS research and development require the input of experts who use different technical languages and come from varying disciplines and backgrounds, scientists and students can avoid potential difficulties in communication and understanding only if they possess a skill set and understanding that enables them to work at the interface of engineering and biosciences. Keeping this duality in mind throughout, BioMEMS: Science and Engineering Perspectives supports and expedites the multidisciplinary learning involved in the development of biomicrosystems. Divided into nine chapters, it starts with a balanced introduction of biological, engineering, application, and commercialization aspects of the field. With a focus on molecules of biological interest, the book explores the building blocks of cells and viruses, as well as molecules that form the self-assembled monolayers (SAMs), linkers, and hydrogels used for making different surfaces biocompatible through functionalization. The book also discusses: Different materials and platforms used to develop biomicrosystems Various biological entities and pathogens (in ascending order of complexity) The multidisciplinary aspects of engineering bioactive surfaces Engineering perspectives, including methods of manufacturing bioactive surfaces and devices Microfluidics modeling and experimentation Device level implementation of BioMEMS concepts for different applications. Because BioMEMS is an application-driven field, the book also highlights the concepts of lab-on-a-chip (LOC) and micro total analysis system (μTAS), along with their pertinence to the emerging point-of-care (POC) and point-of-need (PON) applications.

Clinical Monitoring And Transesophageal Echocardiography
Author: Jeffery S. Vender
Publisher:
Release Date: 2004
Pages:
ISBN:
Available Language: English, Spanish, And French
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Amperometric And Impedance Monitoring Systems For Biomedical Applications
Author: Jaime Punter-Villagrasa
Publisher: Springer
Release Date: 2017-09-13
Pages: 241
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

The book presents the conception and realization of a pervasive electronic architecture for electrochemical applications, focusing on electronic instrumentation design and device development, particularly in electrochemical Point-of-Care and Lab-on-a-Chip devices, covering examples based on amperometric (DC) and impedance detection (AC) techniques. The presented electronics combine tailored front-end instrumentation and back-end data post-processing, enabling applications in different areas, and across a variety of techniques, analytes, transducers and environments. It addresses how the electronics are designed and implemented with special interest in the flow process: starting from electronic circuits and electrochemical biosensor design to a final validation and implementation for specific applications. Similarly, other important aspects are discussed throughout the book, such as electrochemical techniques, different analytes, targets, electronics reliability and robustness. The book also describes the use of the presented electronics in different electrochemical applications through some examples: instantaneous and non-destructive cellular monitoring and portable glucose monitoring device. Moreover, the book aims to introduce a comprehensive approach to electronic circuits, techniques and electrochemical sensors in POC devices to a general audience of students in biomedical and electronics engineering, scientists, and engineers.

Genetic Engineering And Biotechnology Monitor
Author:
Publisher:
Release Date: 1994
Pages:
ISBN:
Available Language: English, Spanish, And French
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An Automated Lab On A CD System For Parallel Whole Blood Analyses
Author: Tingjie Li
Publisher:
Release Date: 2012
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Medical diagnostics plays a critical role in human healthcare. Blood analysis is one of the most common clinical diagnostic assays. Biomedical engineers have been developing portable and inexpensive diagnostic tools that enable fast and accurate tests for individuals who have limited resources in places that require such field applications. The emergence of Lab-on-a-CD technology provides a compact centrifugal platform for high throughput blood analysis in point-of-care (POC) diagnostics. The objective of this thesis work is to develop a Lab-on-a-CD system for parallel quantitative detection of blood contents. Blood separation is a key step in blood analysis. By integrating out-of-plane microvalves into the Lab-on-a-CD system, pure plasma is separated from human whole blood sample for subsequent blood detection. These out-of-plane microvalves show excellent performance in preventing backflow or reverse mixing due to blood cell diffusion. The concentrations of certain blood contents in the separated plasma can be detected using the electrochemical biosensors embedded in the plasma reservoir. To improve sensitivity, a nanoporous structure is created on the surfaces of the biosensors' electrodes through an alloying/dealloying process. The nanoporous electrode has an electroactive surface area up to 60 times larger than that of a flat gold electrode of the same size. As a result, numerous catalysts and enzymes are stably entrapped in the nanoporous structure, leading to high sensitivity, stability and reproducibility of the biosensor. Based on this devised blood separation technique and the improved electrochemical detection method, a Lab-on-a-CD prototype was constructed and successfully applied in the concentration detection of glucose, lactate and uric acid with linear ranges of 0 - 30 mM, 0 - 1.5 mM and 0 - 5 mM, respectively. Furthermore, the volume of whole blood sample consumed for each section can be as small as 16 æL. The Lab-on-a-CD platform developed in this thesis is low-cost, robust, and simple-to-use. Potentially, it could be used in clinical diagnostics and will especially aid developing countries where resources are limited.

Biocommerce Abstracts
Author:
Publisher:
Release Date: 1997
Pages:
ISBN:
Available Language: English, Spanish, And French
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American Laboratory
Author:
Publisher:
Release Date: 2000
Pages:
ISBN:
Available Language: English, Spanish, And French
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