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The last two decades has been the most exciting period in cucurbit genetic, genomic, and breeding research especially for cucumber, melon, and watermelon. In addition, cucumber became the first cucurbit to be sequenced, after other field crops such as rice, sorghum, soybean, and maize. In thirteen chapters by 34 internationally renowned scientists, this book provides an in-depth review of the state of the art of genetic and genomic research conducted in cucurbits. It will be an essential resource for cucurbit researchers as well as scientists working in other crops.
Professors Tom Strachan & Andrew Read awarded the Education Award 2007 of the ESHG for their outstanding contribution to the dispersal of knowledge of modern human molecular genetics among students and professionals. Following the completion of the Human Genome Project the content and organization of the third edition of Human Molecular Genetics has been thoroughly revised. * Part One (Chapters 1-7) covers basic material on DNA structure and function, chromosomes, cells and development, pedigree analysis and the basic techniques used in the laboratory. * Part Two (Chapters 8-12) discusses the various genome sequencing projects and the insights they provide into the organisation, expression, variation and evolution of our genome. * Part Three (Chapters 13-18) focuses on mapping, identifying and diagnosing the genetic causes of mendelian and complex diseases and cancer. * Part Four (Chapters 19-21) looks at the wider horizons of functional genomics, proteomics, bioinformatics, animal models and therapy. There are new chapters on cells and development and on functional genomics. The sections on complex diseases have been completely rewritten and reorganized, as has the chapter on Genome Projects. Other changes include a new section on molecular phylogenetics (Chapter 12) and the introduction of 'Ethics Boxes' to discuss some of the implications of the new knowledge. Virtually every page has been revised and updated to take account of the stunning developments of the past four years since the publication of the last edition of Human Molecular Genetics. Features: * Integration of Human Genome Project data throughout the book * Two new chapters 'Cells and Development' (Chapter 3) and 'Beyond the Genome Project: Functional Genomics, Proteomics and Bioinformatics' (Chapter 19) * Completely rewritten and reorganised coverage of complex disease genetics * Increased emphasis on gene function and on applications of genetic knowledge, including ethical issues * More prominence given to novel approaches to treating disease, such as cell-based therapies, pharmacogenomics, and personalised medicine * Special topic boxes that include detailed coverage of ethical, legal and social issues, including eugenics, genetic testing and discrimination, germ-line gene therapy and genetic enhancement, and human cloning * Contains two indices: a general index and one that contains names of diseases and disorders Supplements: Art of HMG3 (CD-ROM) 0-8153-4183-0: £34.00
Details the history of the study of genetics, from Mendel's discoveries to the decoding of the human genome, and explains the fundamentals of genetics, the function of genes, and DNA manipulation.
Unravels the mysteries of the science of DNA, chromosomes, and genes, as well as to bring to the forefront current methods and theories of genetic inquiry.
The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.
Key to life - Cells - Genes - DNA - Baby blueprint - Genetic traits - Genetic diseases - Nature and nurture - Genetic engineering - Cloning and choosing - Genetic medicine - DNA mapping - DNA debates.
This is the first of a planned two-volume work discussing the mathematical aspects of population genetics with an emphasis on evolutionary theory. This volume draws heavily from the author’s 1979 classic, but it has been revised and expanded to include recent topics which follow naturally from the treatment in the earlier edition, such as the theory of molecular population genetics.
About the Book: Endeavours to make this seemingly difficult subject understandable and enjoyable for the readers. It provides an account of classical and modern genetics with new developments in the field. The scope of each chapter has been broadened enough to provide information on historical landmarks as well as of new facts from current issues of major journals. Chapters on gene transcription, regulation, human genetics, recombinant DNA and genomics have been given special attention to create awareness about future areas in this growing field. Experimental work is supported by methodologie.
A thorough cross-disciplinary exploration of the implications of genomics-influenced educational practice, for consideration by scientists, practitioners and laypersons alike.