gap junction structure and chemical regulation

Gap Junction Structure And Chemical Regulation
Author: Camillo Peracchia
Publisher: Academic Press
Release Date: 2019-02-15
Pages: 200
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension. Contains comprehensive, historical coverage on direct cell-to-cell communication Provides detailed coverage of gap junction channel structure and regulation, with extensive coverage of the direct role of calmodulin in channel gating Delivers a thorough description of models proposed for the chemical gating of gap junction channels

Gap Junction Structure And Chemical Regulation
Author: Camillo Peracchia
Publisher: Academic Press
Release Date: 2019
Pages: 212
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Gap Junction Structure and Chemical Regulation: Direct Calmodulin Role in Cell-to-Cell Channel Gating describes and discusses the findings of major studies conducted during the past century on the structure and chemical regulation of direct cell-to-cell communication via gap junction channels. Chapters bring together important findings on direct cell communication, from its history, to its structure and regulation. These channels are essential for normal organ function, and mutations in their protein (connexin) cause various diseases. The book is useful for established investigators who need a review on the field and young investigators who need a thorough resource for study and comprehension.

Exam Prep For  Gap Junction Structure And Chemical Regulation
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Gap Junctions  Molecular Basis Of Cell Communication In Health And Disease
Author: Dale J. Benos
Publisher: Gulf Professional Publishing
Release Date: 1999-12-28
Pages: 648
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot-Marie-Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas disease.

Cardiac Gap Junctions
Author: Stefan Dhein
Publisher: Karger Medical and Scientific Publishers
Release Date: 1998-01-01
Pages: 148
ISBN:
Available Language: English, Spanish, And French
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Gap Junctions
Author: Rudolf Werner
Publisher: IOS Press
Release Date: 1998
Pages: 385
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This monograph contains research articles from the leading laboratories around the world on gap junctions, the intercellular channels that allow communication between neighbouring cells. It describes the latest results in gap junctions research, the structural and functional characterization of cell-cell channels, the assembly and degradation of gap junctions, the expression and function of gap junctions in different tissues, knockout studies of gap junction genes, the regulation of connexin gene expression, and the functions of gap junctions in development and cancer. Any laboratory interested in intercellular communications and gap junction research will find this monograph an indispensable source of information and reference.

International Review Of Cell And Molecular Biology
Author: Kwang W. Jeon
Publisher: Academic Press
Release Date: 2009-11-02
Pages: 376
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. * Authored by some of the foremost scientists in the field * Provides up-to-date information and directions for future research * Valuable reference material for advanced undergraduates, graduate students and professional scientists

Chemical Induction Of Cancer
Author: Joseph C. Arcos
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
Pages: 712
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

In the approach to the analysis of disease, including, of course, cancer, two major thrusts may be distinguished. These may be referred to, in shorthand, as agents and processes: the causative agents (chemical, microbial, physical, environmental, and psychosocial) and the organismic processes, initiated and furthered by the agents, culminating in observable pathology (at the macromolecular, cytological, histological, organ function, locomotor, and behavioral levels). The past 25 years, since the appearance of the first volume of the predecessor series (1) authored by the Editors of this present volume, have seen an impressive number of studies on chemicals (and other agents) as etiologic factors in the induction of cancer. The major emphasis has been on the discovery of many chemical carcinogens of widely different structures, their metabolism by various tissues and cells, and, in turn, their molecular-biochemical effects on the cells. This rapidly expanded body of information, as effectively covered in the predecessor volumes, is an excellent entree to the second half of the overall problem of chemical carcinogenesis, the processes. The active agents trigger a large array of molecular-biochemical alterations to which the target cells, target tissues, and target organisms respond in many select and common ways. This second major aspect of the induction of cancer by chemicals (and by other agents)- the sequence of cellular and tissue changes clearly relevant to cancer-remains the challenge for the future.

Handbook Of Membrane Channels
Author:
Publisher: Academic Press
Release Date: 2012-12-02
Pages: 591
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

This handbook provides a thorough account of recent directions in membrane channel research. Each subject is covered in terms of channel biophysics, pharmacology, and molecular biology. The introductory chapter reviews methodologies of molecular biology currently used for studying molecular structure and function of membrane channels and specific domains in channel proteins.

Biology Of The Uterus
Author: W. Jollie
Publisher: Springer Science & Business Media
Release Date: 2013-06-29
Pages: 644
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Almost a quarter of a century has elapsed since Cellular Biology of the Uterus, the predecessor of the present volume, was planned. During that period, especially in the decade since the publication of the last edition of Biology of the Uterus, new information in the field has been so voluminous as to require major revisions of most of the chapters, the addition of several new chapters, and the collaboration of a second editor to facilitate the selection of appropriate experts as authors. As in prior editions, a balance has been struck between classical biology and modem biochemistry and biophysics. The inclusion of basic histological and embryo logical information provides a necessary, though often lacking, background for the protein chemist and molecular biologist and a bridge between the cell biologist and clinician. Thus, major practical problems in human reproduction, such as the genesis of endometrial carcinoma and the cause of the initiation of labor, may be approached on a firm scientific footing. The current edition deals primarily with the biology of the uterus itself (comparative and human) rather than placentation or pregnancy and thus is a synthesis of data derived from many techniques, both conventional and modem. As it is clearly beyond the competence of anyone scientist to prepare such a text on the basis of personal knowledge and experience, the aid of 22 distinguished scientists was enlisted.

Inhibition Of Intercellular Communication In Rat Leydig Cells In Vitro By Xenobiotic Chemicals
Author: Hong Hsu
Publisher:
Release Date: 1991
Pages: 170
ISBN:
Available Language: English, Spanish, And French
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Biochemical Mechanisms And Regulation Of Intercellular Communication
Author: Harry A. Milman
Publisher: Princeton Scientific Pub
Release Date: 1987
Pages: 292
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

AGENTS THAT REGULATE GAP JUNCTIONAL CONDUCTANCE: SITES OF ACTION AND SPECIFICITIES; THE ROLE OF ION DEREGULATION IN TOXIC CELL INJURY; ALTERATION OF CELLULAR INTERACTIONS IN THE IMMUNE SYSTEM: NATURAL KILLER CELL ACTIVITY AND N LYMPHOCYTES; NEUROTOXICITY EXPRESSED THROUGH ALTERATIONS OF CELL-CELL INTERACTION; THE IMPORTANCE OF NORMAL CELLULAR COMMUNICATION DURING DEVELOPMENT; ALTERATION OF GAP JUNCTIONS AS A POTENTIAL MECHANISM OF REPRODUCTIVE TOXICITY; GAP JUNCTION MODULATION; POSSIBLE ROLE IN TUMOR CELL BEHAVIOR; CELLULAR COMMUNICATION IN CELL TRANSFORMATION; CHEMICAL AND ONCOGENE MODULATION OF INTERCELLULAR COMMUNICATION IN TUMOR PROMOTION; THE POTENTIAL ROLE OF BIOACTIVATION IN TUMOR PROMOTION, INDIRECT EVIDENCE FROM EFFECTS OF PHENOL SODIUM CYCLAMATE AND THEIR METABOLITES ON METABOLIC COOPERATION IN VITRO; THE EFFECT OF TUMOR PROMOTERS ON CELL TO CELL COMMUNICATION IN LIVER EPITHELIAL CELL SYSTEMS; APPLICATIONS OF THE CHINESE HAMSTER V79 METABOLIC COOPERATION ASSAY IN TOXICOLOGY.

Government Reports Announcements   Index
Author:
Publisher:
Release Date: 1989
Pages:
ISBN:
Available Language: English, Spanish, And French
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Chemical Abstracts
Author:
Publisher:
Release Date: 2002
Pages:
ISBN:
Available Language: English, Spanish, And French
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Pediatric Critical Care E Book
Author: Bradley P. Fuhrman
Publisher: Elsevier Health Sciences
Release Date: 2011-03-24
Pages: 1776
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Provide the latest in superior quality care for critically ill children with the full-color, updated 4th Edition of Fuhrman and Zimmerman’s Pediatric Critical Care. In print, and now online, Drs. Bradley P. Fuhrman and Jerry J. Zimmerman use a comprehensive, organ-systems approach to help you manage a full range of disease entities. Get up-to-the-minute knowledge of topics such as acute lung injury, multiple organ dysfunction syndrome, and more. Implement new clinical techniques and diagnostic tests, weigh the varying perspectives of six associate editors with expertise in the field, reference 1,000+ illustrations to aid diagnosis, and keep sharp with online access to board-style review questions. This definitive title will ensure that you consistently deliver the very best intensive care to your pediatric patients. Focus on the development, function, and treatment of a wide range of disease entities with the text’s clear, logical, organ-system approach. Keep all members of the pediatric ICU team up to date with coverage of topics particularly relevant to their responsibilities. Keep current with the latest developments in palliative care, mass casualty/epidemic disease, acute respiratory failure, non-invasive ventilation, neurocritical care, neuroimaging, hypoxic-ischemic encephalopathy, stroke and intracerebral hemorrhage, systemic inflammatory response syndrome, acute lung injury, multiple organ dysfunction syndrome, and much more. Quickly find the information you need with sections newly reorganized for easier access. Gain the perspectives of six expert associate editors on all the new developments in the field. Understand complex concepts quickly and conclusively with a brand new full-color format and more than 1,000 illustrations. Search the full text, download the image library, and access online board review questions targeting every relevant topic, all at www.expertconsult.com.

Current Topics In Membranes And Transport
Author:
Publisher: Academic Press
Release Date: 1984-09-05
Pages: 377
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Current Topics in Membranes and Transport

Cell To Cell Communication
Author: Walmor C. De Mello
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
Pages: 388
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Gap Junctions  Molecular Basis Of Cell Communication In Health And Disease
Author:
Publisher: Academic Press
Release Date: 1999-12-27
Pages: 648
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot Marie Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas' disease.

Proceedings Of The Society For Experimental Biology And Medicine
Author: Society for Experimental Biology and Medicine (New York, N.Y.)
Publisher:
Release Date: 1991
Pages:
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

List of members in each volume.

Medical Physiology  2e Updated Edition E Book
Author: Walter F. Boron
Publisher: Elsevier Health Sciences
Release Date: 2012-01-13
Pages: 1350
ISBN:
Available Language: English, Spanish, And French
EBOOK SYNOPSIS:

Medical Physiology, in its updated 2nd edition, firmly relates molecular and cellular biology to the study of human physiology and disease. Drs. Walter Boron and Emile Boulpaep and a team of leading physiologists present you with practical, accurate coverage, continually emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 1400 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject. Quickly review important content using prominent boxes included throughout the text to provide clinical examples of disordered physiology. Master difficult concepts with the use of 800 color drawings that feature balloon captions explaining key processes. Find information easily with the intuitive organization by body system and consistent style. Get up-to-date coverage of physiology with updated text and figures. Access the fully searchable text online at www.StudentConsult.com, along with Webnotes, Image Bank, 150 Self-assessment questions, and 10 physiology animations. Stay current thanks to updated material, including a new chapter on Physiology of Aging and a new section on hemostasis. Gain a clear visual understanding with a revised and updated art program of high-quality, full color line drawings and prominently featured clinical examples.